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Early cellular signaling responses to axonal injury.

Lukas(Thomas J),Wang(Ai Ling),Yuan(Ming),N... Cell Commun Signal 2011-07-14

...Socs3) and apoptosis (Bax).,We interpret our studies to indicate that both neurons and glia in the retina have been sign...

Association of interleukin-6 signalling with the muscle stem cell response fo...

McKay(Bryon R),De Lisio(Michael),Johnston(... PLoS One 2011-08-17

...SOCS3) mRNA were measured using quantitative RT-PCR and serum IL-6 protein was measured using an ELISA kit. JAK2 and STA...

Suppression of SOCS3 in macrophages prevents cancer metastasis by modifying m...

Hiwatashi(Kiyokazu),Tamiya(Taiga),Hasegawa... Cancer Lett 2011-09-02

...SOCS3) has been shown to be a negative regulator of STAT3. In this study, we used macrophage specific SOCS3 conditional ...

Activation of peroxisome proliferator-activated receptor-β/-δ (PPAR-β/-δ) ame...

Serrano-Marco(Lucía),Rodríguez-Calvo(Ricar... Diabetes 2011-08-29

...SOCS3). We evaluated whether peroxisome proliferator-activated receptor (PPAR)-β/-δ prevented activation of the IL-6-STA...

Litter size variation in hypothalamic gene expression determines adult metabo...

Zhang(Xue-Ying),Zhang(Qiang),Wang(De-Hua) PLoS One 2011-09-29

...SOCS3) mRNA in adulthood increased in small litters compared to that in large litters. As a result, the agouti-related p...

Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-infla...

Piantadosi(Claude A),Withers(Crystal M),Ba... J Biol Chem 2011-07-01

...Socs3, or bcl-x(L) gene expression. These findings disclose a highly structured transcriptional network that couples mit...

The PPE18 protein of Mycobacterium tuberculosis inhibits NF-κB/rel-mediated p...

Nair(Shiny),Pandey(Akhilesh Datt),Mukhopad... J Immunol 2011-07-05

...SOCS3), and the phosphorylated SOCS3 physically interacts with IκBα-NF-κB/rel complex, inhibiting phosphorylation of IκB...

[The role of inflammation in the development of insulin resistance in type 2 ...

Usui(Isao),Tobe(Kazuyuki) Nihon Rinsho 2011-05-03

...SOCS3 and the activation of JNK or NFkappaB signaling in insulin-target tissues. They are mainly produced by the classic...

SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gli...

Lindemann(Carina),Hackmann(Oliver),Delic(S... Acta Neuropathol 2011-11-02

...SOCS3 alterations and found frequent SOCS3 promoter hypermethylation and transcriptional downregulation. However, SOCS3 ...

Lentiviral vector-mediated knockdown of SOCS3 in the hypothalamus protects ag...

Liu(Z-J),Bian(J),Zhao(Y-L),Zhang(X),Zou(N)... Diabetes Obes Metab 2011-12-07

...SOCS3 would attenuate diet-induced obesity in rats.,First we established hypothalamic SOCS3-deficient rats through lenti...

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