...AIM2), molecular simulation results further confirmed the stability, structural compactness and residual flexibility. In...
...AIM2, and NOD-like receptor protein 3 pathways. Interleukin-1β (IL-1β) secretion and pro-IL-1β expression were subsequen...
...AIM2 signaling pathway in THP‑1 cells but not in HBEpiCs. However, overexpression of AIM2 in THP‑1 cells markedly revers...
...Aim2) detects double-stranded DNA in the cytosol of infected cells and subsequently assembles a multiprotein complex kno...
...AIM2-related pathways. Beyond cell-intrinsic effects, NF-κB also mediates glial crosstalk and contributes to endothelial...
...AIM2 to drive type I interferon and pro-inflammatory cytokine responses. In the adaptive immune system, eccDNA is not me...
...AIM2 inflammasome pathway. GA did not aggravate HMGB1 knockdown induced cell cycle arrest, DNA damage, and pyroptosis. G...
...AIM2/RIPK3/CASP1 death complex and inhibiting the TLR4/NLRP3 survival signaling axis. This study systematically revealed...
...Aim2) and downstream effector genes (Casp-1, Casp-11/4, Il1b, and Il18) across the prefrontal cortex, hippocampus, and s...
...AIM2 signaling, as shown by immunoblotting and biophysical analyses. Mechanistic studies demonstrated direct NLRP3 bindi...
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