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Osteopathia striata with cranial sclerosis, associated with juvenile idiopath...

Yakovlev(AA),Gaidar(EV),Suspitsin(EN),Korz... World J Orthop 2026-02-18

...AMER1 c.800C>A (p.Ser267*) variant, which was not detected in the healthy mother. Thus, the diagnosis of OSCS was made b...

Systematic Review: Prognostic Molecular Biomarkers in Wilms Tumors.

Oller(A),Kemmeren(P),Perotti(D),van Tinter... JCO Precis Oncol 2026-05-00

...AMER1, CTNNB1, GPC3, MLLT1, DICER1, DIS3L2). Outcome included relapse-free survival, event-free survival (EFS), and over...

Tumoral AMER1 driven dopamine synthesis triggers cancer cell pyroptosis and l...

Dang(JL),Hu(Q),Lu(Y),Wang(J),Li(X),Chen(Y)... Cancer Lett 2026-08-03

...AMER1) downregulation correlates with advanced progression and cytotoxic CD8+ T cell spatial exclusion in CRC patients. ...

Identification of a Novel AMER1 Variant and Craniofacial Phenotypic Spectrum ...

Chen(Q),Wang(X),Liu(N),Yuan(W),Song(Y) Am J Med Genet A 2026-09-00

...AMER1 gene, characterized primarily by generalized skeletal sclerosis and striated changes. However, research on its cra...

Artificial Intelligence-Enabled Analysis of WNT Pathway Dysregulation in Beva...

Ruiz-Garcia(E),Waldrup(B),Carranza(FG),Man... Int J Mol Sci 2026-07-11

...AMER1, suggesting potential biologic interaction or treatment-related selective pressure. Importantly, WNT pathway alter...

[Analysis of clinical characteristics and genetic etiology of a child with Os...

Zhang(H),Yin(W),Wang(Y),Chen(B),Gao(C),Liu... Zhonghua Yi Xue Yi Chuan Xu... 2025-09-10

...AMER1 gene. A child presented at the Affiliated Children's Hospital of Zhengzhou University in July 2024 due to growth a...

Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Can...

Sanz-Pamplona(Rebeca),Lopez-Doriga(Adriana... Clin Cancer Res 2016-08-01

...AMER1 (also known as FAM123B or WTX) gene emerged as recurrent mutations in colorectal cancer. Losses of AMER1 by other ...

Genetic and chromosomal alterations in Kenyan Wilms Tumor.

Lovvorn(Harold N),Pierce(Janene),Libes(Jai... Genes Chromosomes Cancer 2016-06-13

...AMER1 in 5 (11%), WT1 and TOP2A in 4 (9%), and IGF2 in 3 (7%). Loss of heterozygosity (LOH) at 17p, which covers TP53, w...

Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragmen...

Zhang(Zhenyi),Akyildiz(Senem),Xiao(Yafei),... Cell Discov 2016-07-27

...Amer1/WTX, which is mutated in Wilms' tumor and bone overgrowth syndrome. The APC-Amer1 complex has important roles in r...

β-arrestin promotes Wnt-induced low density lipoprotein receptor-related prot...

Kríz(Vítezslav),Pospíchalová(Vendula),Mase... J Biol Chem 2014-04-08

...Amer1/WTX/Fam123b. Amer1 has been shown very recently to bridge Wnt-induced and Dishevelled-associated PtdIns(4,5)P2 pro...

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