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Cotranslational assembly directs the biogenesis of the m6A methyltransferase ...

Wu(X),Zhang(H),Huang(L),Zhang(S),He(J),Wan... Proc Natl Acad Sci U S A 2026-01-06

...CCT4, the key subunit of cytosolic chaperonin TCP-1, as an essential facilitator of the endogenous MTC assembly process....

TRiC-assisted folding of class I HDAC family proteins regulated by distinct c...

Li(Z),Zhao(Q),Jiang(W),Song(Q),Zhou(X),Shi... Sci Adv 2026-07-17

...CCT4 in TRiC-HDAC1 complex that may relate to co-chaperone release. By contrast, HDAC8 folds independently of TRiC. Toge...

Over-Expression Analysis of All Eight Subunits of the Molecular Chaperone CCT...

Spiess(Matthias),Echbarthi(Meriem),Svanstr... J Mol Biol 2015-11-20

...Cct4, rescues growth of the temperature-sensitive strain cct4-1 at the non-permissive temperature, indicative of conserv...

Silencing of long noncoding RNA MALAT1 by miR-101 and miR-217 inhibits prolif...

Wang(Xinyu),Li(Meng),Wang(Zhiqiong),Han(Si... J Biol Chem 2015-05-08

...CCT4, and CTHRC1. A significant negative correlation exists between miR-101 or miR-217 and MALAT1 in 42 pairs of ESCC ti...

Serum antibody response to group II chaperonin from Methanobrevibacter oralis...

Hirai(Kimito),Maeda(Hiroshi),Omori(Kazuhir... Pathog Dis 2014-04-28

...CCT4 and CCT8 on dot blot analysis. Signals for CCT3 and CCT8 in autoimmune disease patients were significantly higher t...

Biochemical characterization of mutants in chaperonin proteins CCT4 and CCT5 ...

Sergeeva(Oksana A),Tran(Meme T),Haase-Pett... J Biol Chem 2014-12-17

...CCT4 soluble subunits. Electron microscopy of negatively stained samples of C450Y CCT4 revealed few ring-shaped species,...

Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form bi...

Sergeeva(Oksana A),Chen(Bo),Haase-Pettinge... J Biol Chem 2013-08-21

...CCT4 and CCT5, but not the other six CCT subunits, formed high molecular weight complexes within the E. coli cells that ...

Analyzing microarray data of Alzheimer's using cluster analysis to identify t...

Guttula(Satya Vani),Allam(Apparao),Gumpeny... Int J Alzheimers Dis 2012-08-23

...CCT4, IGF2R, SFPQ, PRDX3, RNF14, IDS, SSBP1, SYNE2, TXNL4A, STXBP3, SMARCB1, ULK2, AGTPBP1, FABP7, CALB1, H2AFY, COPA, S...

Molecular targets for diabetes mellitus-associated erectile dysfunction.

Yohannes(Elizabeth),Chang(Jinsook),Tar(Mos... Mol Cell Proteomics 2010-07-13

...Cct4, Cct5, and Sepina3n), proteins that neutralize the biological activity of nerve growth factor (e.g. anti-NGF 30), a...

MALAT-1 enhances cell motility of lung adenocarcinoma cells by influencing th...

Tano(Keiko),Mizuno(Rie),Okada(Tomoko),Rakw... FEBS Lett 2010-12-20

...CCT4, HMMR, or ROD1 clearly inhibited cell migration. In MALAT-1 knockdown cells, pre-mRNA levels were decreased in some...

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