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In-silico identification of genetic variants associated with chronic lymphocyti…

Islam(MS),Mollah(MMH),Ahsan(MA),Ali(M),Al No… Sci Rep 2026-03-23

...CFLAR, CASP8, and LEF1) as the CLL-associated key genes (KGs) by the protein-protein interaction (PPI) network analysis....

Targeting RSF1 with tanshinone I inhibits cervical cancer cell growth through m…

Shen(Y),Lu(S),Zhao(Q),Cui(T),Cui(H),Cui(Z),S… Front Pharmacol None

...CFLAR, BCL2, and BIRC2. Moreover, Tan I enhances the cytotoxic activity of carboplatin when used in combination. Togethe...

The Curcumin Analogue PAC Induces Selective Apoptosis-Related Transcriptomic Re…

Benchekroun(S),Hammache(M),Chandad(F),Almuta… Life (Basel) 2026-06-23

...CFLAR, and NFKB1. In contrast, CAL27 cells exhibited a more pronounced pro-apoptotic transcriptional profile characteriz...

CRISPR screens identify PRMT7 as a therapeutic target to enhance T cell-mediate…

Shi(W),Luo(Y),Wang(Y),Burrows(JM),Black(D),C… NPJ Breast Cancer 2026-01-21

...CFLAR, CREBBP and PRMT7 enhanced sensitivity. Analysis of clinical data showed that PRMT7 expression is negatively corre...

Expression of cFLIP in B cells is essential for diffuse large B-cell lymphoma p…

Bariboloka(KT),Serrano-Saenz(S),Savcigil(DP)… Blood 2026-08-20

...Cflar, the gene encoding for cFLIP, prevented lymphomagenesis mediated by oncogenic Myd88 and overexpression of BCL2. In...

Single-cell analysis reveals the prognostic role of immune escape in the colore…

Gan(Q),Xu(X),Liu(H),Li(Y) Transl Cancer Res 2026-01-31

...CFLAR+B_cells-C3, CALR+CD8+T_cells-C2, and TAP1+Mac-C2 may serve as potential biomarkers for predicting responses to imm...

Single-cell RNA-seq reveals the piperlongumine is a potential drug for ischemic…

Li(J),Zhu(X),Zhang(Y),Xu(Z),Zhuang(Y),Chen(L… PLoS One None

...Cflar. Finally, in vitro and in vivo experiments conformed the effectiveness of piperlongumine. This study provided new ...

Higher frequencies of CNV deletions in bipolar disorder among Chinese Populatio…

Wu(Y),Li(X),Sun(Y),Zhang(C),Sun(P),Hui(L),Zh… Mol Psychiatry 2026-08-27

...CFLAR at 2q33.1, alongside a duplication affecting ZNF878 and ZNF844 at 19p13.2. These disrupted genes are chiefly impli...

MAFF mediates transcriptional activation of CFLAR to reduce regulatory T cell a…

Kang(X),Li(J),Cao(Y) Tissue Cell 2026-06-23

...CFLAR, and the transcriptional regulation between MAFF and CFLAR was verified. Tregs and DR mice were treated with MAFF ...

Physiological Effects of Dietary Protein and Its Optimal Requirement for Early …

Zhang(L),Chen(X),Huang(D),Zhou(Q),Xu(X),Ren(… Animals (Basel) 2026-06-18

...cflar, bcl-2, and tradd, downregulated bax, casp9, and casp3. Quadratic regression analysis using WGR and FCR as indices...

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