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Integrated analysis of glutamine metabolism and immune microenvironment identif…

Pan(X),Ye(T),Liu(J),Zheng(X) Discov Oncol 2026-02-12

...GOT2, FAH, LAT, and SLC7A11) were identified for constructing a risk score model for HNSCC patients. High expression lev...

Comparative transcriptome analysis of kiwifruit reveals candidate genes involve…

Lv(D),Li(Y),Zuo(X),Yang(J),Tu(G),Wang(J),Cai… J Sci Food Agric 2026-05-00

...GOT2, 4CL, CHS, CHI, CCR, F5H, BGLU, BGLU2, BGLU4, POD12, POD55), calcium (Ca2+) signaling pathway (CALM2, CML23), trans...

Circadian tryptophan metabolism contributes to systemic aryl hydrocarbon recept…

Morgan(EW),Murray(IA),Coslo(DM),Patterson(AD… iScience 2026-02-20

...GOT2, KAT1, KAT2, and IL4I1) and serum tryptophan metabolites (indole-3-acetate, indole-3-lactate, indole-3-propionate, ...

Proteomic and amino acid profiling of SK-MEL-30 melanoma reveals metabolic and …

Turker(NP) Anal Biochem 2026-11-00

...GOT2 expression, suggest an active glutamine aspartate axis supporting tricarboxylic acid cycle activity and nitrogen me...

A shift in the cellular redox state redirects aspartate for export under glucos…

Konrad(B),Bluemel(G),Haitzmann(T),Frech(T),V… Cancer Metab 2026-03-03

...GOT2) decreased aspartate release. Low glucose conditions diminished reduced nicotinamide adenine dinucleotide (NADH) an...

A tryptophan metabolism-related gene signature predicts prognosis and immune fe…

Zhao(L),Li(ZC),Tang(ZY),Yuan(YT),Zhu(S) Front Immunol None

...GOT2, STAT1, CAT, and IDO1, divided patients into high- and low-risk groups with significantly different overall surviva...

Dietary resveratrol improves meat quality and antioxidant capacity of Tibetan s…

Li(X),Lu(Z),Yuan(C),Zheng(C),Liu(T),Chen(B),… Front Nutr None

...GOT2) and differential metabolites (4-methylene-L-glutamine, anserine, betaine aldehyde, and N1-Methyl-2-pyridone-5-carb...

Hypoxia-induced PLOD3 activates the NEDD4/GOT2 axis to exacerbate renal cell ca…

Xu(Y),Lun(Y),Wang(S),Jiao(Y),Shen(S),Yan(Y),… Cell Death Dis 2026-06-10

...GOT2 expression via inducing K48-linked ubiquitination, leading to GOT2 degradation via the ubiquitin-proteasome pathway...

Differential expression of metabolic genes distinguishes physiological from pat…

Cai(X),Lin(S),Chen(J),Dai(Q),Diao(Y),Zheng(L) BMC Cardiovasc Disord 2026-06-13

...GOT2 as key hub genes. In vivo and in vitro experiments demonstrated that these genes were significantly upregulated in ...

Integrating bulk RNA-seq, Mendelian randomization and single-cell RNA-seq to el…

Wang(Y),Wang(X) Front Immunol None

...GOT2, PYGL, and SLC25A4. The ANN model demonstrated excellent diagnostic performance across independent cohorts (AUC > 0...

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