...GOT2, FAH, LAT, and SLC7A11) were identified for constructing a risk score model for HNSCC patients. High expression lev...
...GOT2, 4CL, CHS, CHI, CCR, F5H, BGLU, BGLU2, BGLU4, POD12, POD55), calcium (Ca2+) signaling pathway (CALM2, CML23), trans...
...GOT2, KAT1, KAT2, and IL4I1) and serum tryptophan metabolites (indole-3-acetate, indole-3-lactate, indole-3-propionate, ...
...GOT2 expression, suggest an active glutamine aspartate axis supporting tricarboxylic acid cycle activity and nitrogen me...
...GOT2) decreased aspartate release. Low glucose conditions diminished reduced nicotinamide adenine dinucleotide (NADH) an...
...GOT2, STAT1, CAT, and IDO1, divided patients into high- and low-risk groups with significantly different overall surviva...
...GOT2) and differential metabolites (4-methylene-L-glutamine, anserine, betaine aldehyde, and N1-Methyl-2-pyridone-5-carb...
...GOT2 expression via inducing K48-linked ubiquitination, leading to GOT2 degradation via the ubiquitin-proteasome pathway...
...GOT2 as key hub genes. In vivo and in vitro experiments demonstrated that these genes were significantly upregulated in ...
...GOT2, PYGL, and SLC25A4. The ANN model demonstrated excellent diagnostic performance across independent cohorts (AUC > 0...
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