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A therapeutically targetable positive feedback loop between lnc-HLX-2-7, HLX, a…

Katsushima(K),Joshi(K),Yuan(M),Romero(B),Bat… Cell Rep 2024-00-26

...HLX-2-7 RNA specifically accumulates in the promoter region of HLX, a sense-overlapping gene of lnc-HLX-2-7, which activ...

The H2.0-like homeobox transcription factor modulates yolk sac vascular remodel…

Prahst(Claudia),Kasaai(Bahar),Moraes(Filipa)… Arterioscler Thromb Vasc Biol 2014-08-26

...HLX in vascular development in mouse and avian embryos.,In situ hybridization showed that Hlx is expressed in a subset o...

LncRNA-HLX-2-7/HLX axis-dependent metabolic reprogramming drives cancer progres…

Katsushima(K),Sanada(Y),Scott(DA),Stapleton(… Acta Neuropathol Commun 2026-03-19

...HLX as a downstream effector of lnc-HLX-2-7. These results highlight a coordinated lnc-HLX-2-7/HLX axis that regulates m...

Homeodomain protein HLX is expressed primarily in cytotrophoblast cell types in…

Rajaraman(Gayathri),Murthi(Padma),Quinn(Leon… Reprod Fertil Dev 2008-06-26

...HLX homeobox gene (previously known as HLX1 and HB24) is important for normal placentation. We have previously shown tha...

Over-expression of Hlx homeobox gene in DC2.4 dendritic cell enhances its matur…

Shotorbani(Siamak Sandoghchian),He(Zhiqiang)… Cell Immunol 2012-06-29

...Hlx-over-expressed dendritic cell line (DC2.4/Hlx), and investigated the possible effect of Hlx gene on maturation of de...

A TBX2-HLX Regulatory Axis Is Associated with Advanced Prostate Cancer.

Raju(M),Motakatla(PI),Khedmatgozar(H),Nandan… Biomedicines 2026-08-20

...HLX) in prostate cancer (PCa) remains poorly defined. We investigated the clinical significance of HLX and its relations...

Comparative genomics of the Hlx homeobox gene and protein: conservation of stru…

Bates(Michael D),Wells(James M),Venkatesh(By… Gene 2005-08-05

...Hlx gene and protein sequences and expression patterns would be conserved among vertebrates. Comparison of the Hlx gene ...

Homeobox gene HLX is a regulator of HGF/c-met-mediated migration of human troph…

Rajaraman(Gayathri),Murthi(Padma),Brennecke(… Biol Reprod 2011-01-19

...HLX mRNA and protein expression. HLX inactivation significantly decreased trophoblast migration but not invasion. When H...

The Potential Dual Role of H2.0-like Homeobox in the Tumorgenesis and Developme…

Chen(S),Zhang(L),Wang(K),Huo(J),Zhang(S),Zha… Can J Gastroenterol Hepatol 2023-00-00

...HLX) is highly expressed in several hematopoietic malignancies. However, the role of HLX in the carcinogenesis and progr...

[Functional study of transcription factor Hlx modified dendritic cell line DC2.…

Zhou(Cheng-lin),Su(Zhao-liang),Zhu(Jin-lian)… Xi Bao Yu Fen Zi Mian Yi Xue … 2011-06-22

...Hlx into mouse dendritic cell line DC2.4 and observe the effect of hlx on function of dendritic cells.,The eukaryotic ex...

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