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Altered transposon element-derived genes distort oxygen-free radical scavenge...

Suganuma(T),Hassan(H),Swanson(SK),Laxman(S... NAR Mol Med 2026-01-00

...MOCS3) and selenocysteine lyase (SCLY) stabilize the association of Kelch-like ECH-associated protein 1 (KEAP1) with PGA...

A prevalent MOCS2 variant in the Roma population is associated with a novel m...

Cho(SK),Schwarz(G),Tasic(V),Křížková(M),Kr... Eur J Pediatr 2025-07-25

...MOCS3, or GEPH genes. Here, we described five Roma patients from four unrelated families with hypouricemia, accumulation...

Urmylation and tRNA thiolation functions of ubiquitin-like Uba4·Urm1 systems ...

Jüdes(André),Ebert(Folke),Bär(Christian),T... FEBS Lett 2015-05-20

...MOCS3. As judged from biochemical and genetical assays, hURM1 and hUBA4 are functional in yeast, albeit at reduced effic...

Characterization and interaction studies of two isoforms of the dual localize...

Fräsdorf(Benjamin),Radon(Christin),Leimküh... J Biol Chem 2015-02-12

...MOCS3, suggesting a dual function of TUM1 both in sulfur transfer for the biosynthesis of the molybdenum cofactor, and f...

The L-cysteine desulfurase NFS1 is localized in the cytosol where it provides...

Marelja(Zvonimir),Mullick Chowdhury(Mita),... PLoS One 2013-10-22

...MOCS3 in the cytosol of human cells. Here, we present direct data to show the interaction of NFS1 and MOCS3 in the cytos...

Dual role of the molybdenum cofactor biosynthesis protein MOCS3 in tRNA thiol...

Chowdhury(Mita Mullick),Dosche(Carsten),Lö... J Biol Chem 2012-07-23

...MOCS3 is shared between both pathways. MOCS3 has an N-terminal adenylation domain and a C-terminal rhodanese-like domain...

The dual role of ubiquitin-like protein Urm1 as a protein modifier and sulfur...

Wang(Fengbin),Liu(Meiruo),Qiu(Rui),Ji(Chao... Protein Cell 2012-04-25

...MOCS3, through a mechanism involving the E1-like protein Uba4 (MOCS3 in humans). Similar to ubiquitination, urmylation r...

Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed pro...

Van der Veen(Annemarthe G),Schorpp(Kenji),... Proc Natl Acad Sci U S A 2011-03-23

...MOCS3, ATPBD3, and CTU2). Second, Urm1 is conjugated to the nucleocytoplasmic shuttling factor cellular apoptosis suscep...

Functional deficiencies of sulfite oxidase: Differential diagnoses in neonate...

Sass(Jörn Oliver),Gunduz(Aysegul),Araujo R... Brain Dev 2010-10-08

...MOCS3 and GEPH and result in combined deficiencies of the enzymes sulfite oxidase, xanthine dehydrogenase and aldehyde o...

A novel role for human Nfs1 in the cytoplasm: Nfs1 acts as a sulfur donor for...

Marelja(Zvonimir),Stöcklein(Walter),Nimtz(... J Biol Chem 2008-10-23

...MOCS3-RLD and that sulfur is transferred from L-cysteine to MOCS3-RLD via an Nfs1-bound persulfide intermediate. Because...

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