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Genetic modulators of metabolic dysfunction-associated steatotic liver diseas...

Arriaga-González(FG),de Jesús Castañeda-Có... BMC Med Genomics 2026-03-02

...MTARC1 offer protective effects, reducing the risk of severe liver disease despite comorbidities such as obesity, and ca...

Divergence of the CYB5R3-mARC1 Redox Axis Across the Human MASLD-to-Hepatocel...

Nam(SW) Int J Mol Sci 2026-08-31

CYB5R3 (NADH-cytochrome b5 reductase 3) and mARC1, the product of MTARC1, draw on the same cytochrome-b5 electron relay,...

Beyond Fat: Reframing MASLD Through Genetics, Clonal Biology, and Precision H...

Crespo(J),Alonso-Peña(M),Jiménez-González(... Pharmaceuticals (Basel) 2026-07-24

...MTARC1, GPAM, and CIDEB-have substantially expanded the mechanistic understanding of disease heterogeneity and hepatocel...

LiRNA: An interactive atlas of human liver RNAseq databases.

Alvarez-Sola(G),Shrestha(N),Benedé-Ubieto(... JHEP Rep 2026-08-00

...MTARC1 rs2642438). We then systematically evaluated the generalizability of 64 previously reported gene-phenotype and ge...

Genome-Wide Association Studies in Hepatocellular Carcinoma: Aetiology-Specif...

Zhang(S),Long(X) Genes (Basel) 2026-06-30

...MTARC1. Recent studies increasingly combine GWASs with fine-mapping, functional annotation, transcriptomic analyses, and...

Sex- and mouse strain-related differences in body weight gain, composition of...

Unrug-Bielawska(K),Dziełak(M),Sandowska-Ma... BMC Gastroenterol 2026-02-04

...Mtarc1/2-deficient mice that are resistant to diet-induced obesity; however, the impact of Mtarc1/2 knockout (KO) on the...

MTARC1 p.A165 ablation reduces hepatocellular carcinoma aggressiveness in vit...

Kovooru(L),Zhang(J),Monni(FG),Dutta(T),Gon... Clin Mol Hepatol 2026-04-00

...MTARC1 in HCC is unclear. Therefore, we sought to decipher the role of MTARC1 in HCC. We investigated the role of MTARC1...

Polymorphism's MBOAT7 as Risk and MTARC1 as Protection for Liver Fibrosis in ...

Rocha(S),Oliveira(CP),Stefano(JT),Yokogawa... Int J Mol Sci 2025-07-03

...MTARC1) gene. We also evaluated TM6SF2 rs58542926, GCKR rs1260326 and rs780094, and HSD17B13 rs72613567 and they were no...

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