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Mitochondrial-targeted nano-enhancer driving a self-amplifying NAD+ feedback ...

Li(H),Liu(X),Li(W),Schreiber(AC),Park(S),H... Biomaterials 2027-01-00

...NAMPT) and the mitochondrial transporter SLC25A51, which cooperatively accelerate NAD+ salvage biosynthesis and mitochon...

Host Cell Central Carbon Metabolism and Cellular NAD+ Pool Regulate Efficient...

Pandey(KK),Sahoo(BR),McVey(DS),Pattnaik(AK... Viruses 2026-03-06

...NAMPT inhibitor FK866 suggested NAD+ availability as a critical determinant of VSV replication. Additionally, blockade o...

METTL1-deficient mesenchymal stem cells protect against metabolic-associated ...

Du(J),Zhang(Y),Wang(C),Wang(Y),Zhang(H),Zh... Stem Cells Transl Med 2026-03-23

...NAMPT, which activates SIRT1, leading to the inhibition of SREBP1-mediated lipogenic genes. Inhibition of NAMPT reversed...

Preliminary evidence that blood extracellular nicotinamide phosphoribosyltran...

Benedetti(F),Branchi(I),Shin(HK),Lorenzi(C... Int Clin Psychopharmacol 2026-09-01

...NAMPT) in antidepressant response. NAMPT is the major regulator of the cellular availability of nicotinamide adenine din...

NAMPT inhibition induces ferroptosis via mitochondrial metabolic reprogrammin...

Zhao(D),Duan(L),Ren(H),Zhang(H),Zhang(M),L... Front Immunol None

...NAMPT), a key enzyme in the NAD+ salvage pathway, is highly expressed in glioblastoma and represents a promising metabol...

Neuroprotective effects of salidroside against cerebral ischemia-reperfusion ...

Zhang(M),Xue(J),Ping(Y),Li(H) Front Pharmacol None

...NAMPT, and MCAO+eNAMPT+SAL groups. Recombinant NAMPT (5 μg/rat) and/or SAL (10 μg/rat) were administered intracerebroven...

Discovery of a Nicotinamide Phosphoribosyltransferase (NAMPT) Activator for I...

Li(Y),Yang(S),Fang(Y),Li(Y),Xia(Z),Sheng(C... J Med Chem 2026-05-14

...NAMPT) is the key rate-limiting enzyme in the NAD+ biosynthesis. Herein, we designed and synthesized a series of novel p...

NAD+ precursor supplementation reverses CD36-mediated lipid accumulation and ...

Shi(L),Huang(X),Han(X),Ning(C),Zhao(X),Li(... Pharm Sci Adv 2026-12-00

...NAMPT and NAD+ levels, and rescue assays involved nicotinamide mononucleotide (NMN). For in vivo validation, a murine ly...

Impact of acute blue light irradiation on the molecular clock and markers ass...

Vibriani(A),Chen(X),Kajiwara(S),Orihara(K) J Mol Med (Berl) 2026-04-07

...NAMPT). Remarkably, we found that blue light irradiation disrupted the circadian rhythm at the cellular level. This is e...

Lactobacillus salivarius li01 alleviates premature ovarian insufficiency via ...

Yao(L),Xie(S),Zhang(S),Ba(F),Jing(H),Qiu(B... NPJ Sci Food 2026-04-08

...NAMPT, while attenuating NAD⁺ depletion through downregulation of CD38 expression. The elevated NAD⁺ levels subsequently...

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