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Autoregulation of Pax6 in neuronal cells is mediated by Pax6(5a), Pax6(ΔPD), SP…

Shukla(S),Mishra(R) Mol Biol Rep 2022-04-00

...Pax6 isoforms: Pax6, Pax6(5a), and Pax6(ΔPD); and the two co-expressed Pax6-interacting partners: SPARC and p53 in norma...

Functional interactions between alternatively spliced forms of Pax6 in crystall…

Chauhan(BK),Yang(Y),Cveklová(K),Cvekl(A) Nucleic Acids Res 2004-00-00

...Pax6 proteins [PAX6, mutated PAX6, PAX6(5a) and mutated PAX6(5a)] modeling haploinsufficiency yielded results not predic...

Positive autoregulation of the transcription factor Pax6 in response to increas…

Pinson(J),Simpson(TI),Mason(JO),Price(DJ) BMC Dev Biol 2006-05-25

...Pax6 or Pax6(5a) contained raised levels of both Pax6 and Pax6(5a). Quantitative RT-PCR confirmed an increase in levels ...

Functional properties of natural human PAX6 and PAX6(5a) mutants.

Chauhan(BK),Yang(Y),Cveklová(K),Cvekl(A) Invest Ophthalmol Vis Sci 2004-02-00

...PAX6 are specific DNA-binding proteins, PAX6 and PAX6(5a). PAX6(5a) contains a short insertion influencing its DNA-bindi...

The expression of Pax6 variants is subject to posttranscriptional regulation in…

Shi(F),Fan(Y),Zhang(L),Meng(L),Zhi(H),Hu(H),… PLoS One 2013-00-00

...Pax6 protein is likely to be controlled by the EGFR-ERK pathways. An abnormal increase in Pax6 expression and the Pax6/P...

Histopathological characterisation of effects of the mouse Pax6(Leca4) missense…

Ramaesh(T),Williams(SE),Paul(C),Ramaesh(K),D… Exp Eye Res 2009-08-00

...Pax6 alleles that are functionally equivalent to Pax6(-) null alleles (such as Pax6(Sey) and Pax6(Sey-Neu)) and human in...

Functional analysis of missense mutations G36A and G51A in PAX6, and PAX6(5a) c…

Shukla(S),Mishra(R) Exp Eye Res 2011-07-00

...PAX6-G36A and PAX6-G51A mutants were found to have higher ability to transactivate whereas PAX6(5a)-G36A and PAX6(5a)-G5...

3T3 cell lines stably expressing Pax6 or Pax6(5a)--a new tool used for identifi…

Kiselev(Y),Eriksen(TE),Forsdahl(S),Nguyen(LH… PLoS One 2012-00-00

...Pax6 and Pax6(5a), we generated FlpIn-3T3 cell lines stably expressing Pax6 or Pax6(5a). RNA was harvested from these ce...

Pax6-5a promotes neuronal differentiation of murine embryonic stem cells.

Shimizu(N),Watanabe(H),Kubota(J),Wu(J),Saito… Biol Pharm Bull 2009-06-00

...Pax6 isoforms, Pax6 and Pax6-5a. Pax6-5a differs from Pax6 by the presence of 14 additional amino acids encoded by exon ...

PAX6, paired domain influences sequence recognition by the homeodomain.

Mishra(R),Gorlov(IP),Chao(LY),Singh(S),Saund… J Biol Chem 2002-12-20

...PAX6 on either end of the 5a-polypeptide insert of the alternatively spliced form of PAX6, PAX6-5a. Another PAX6 mutant ...

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