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Non-gonadal PIWIL1/Aubergine drives regenerative and tumorigenic stem cell pr...

Bellec(K),Carroll(LR),Pennel(KAF),Tian(Y),... Cell Rep 2026-03-26

...PIWIL1 mediate tumorigenic intestinal growth in Drosophila and human organoids, respectively. Our results reveal regulat...

Integrated small and long RNA sequencing reveals piRNA mediated transposon re...

Zhang(F),Zhang(H),Xiao(Y),Liu(M),Ren(A),Li... Nat Commun 2026-03-11

...PIWIL1- and PIWIL2-associated long piRNAs correlate with the downregulation of certain specific ERV subfamilies. Genomic...

PIWIL2 drives stroke progression via modulation of NF-κB signaling.

Patil(RM),Laudati(G),Guida(N),Ruggiero(S),... Mol Ther Nucleic Acids 2026-09-08

...PIWIL1 and PIWIL2 were significantly upregulated in the cortex and striatum at 24 h post-ischemia, with PIWIL2 also incr...

Spastic and non-spastic spinal cord injury induce systemic reproductive impai...

Guha(L),Kumar(H) J Spinal Cord Med 2026-08-20

...PIWIL1, and TNP1. These changes were accompanied by reductions in sperm viability, count, and motility, together with in...

Dysregulation of piRNA biogenesis-associated proteins in cancer: mechanisms, ...

Peng(S),Wei(B),Li(X),Li(E) Front Mol Biosci None

...PIWIL1-4, PLD6/MitoPLD, MOV10L1, DDX4/VASA, GASZ, TDRKH, PNLDC1, HENMT1, Tudor-domain proteins, HSP90, and MAEL. We then...

P-Element-Induced Wimpy Testis (PIWI)-Interacting RNA-823/PIWIL1/DNMT3B/CDH1 ...

Shaker(FH),Sanad(EF),Ibrahim(NM),Elghazaly... Int J Mol Sci 2026-01-14

...PIWIL1)/DNA methyltransferase 3B (DNMT3B)/E-cadherin (CDH1) axis in OC tissues from 40 patients, with 20 non-cancer cont...

A novel role of E2F transcription factor 1 in pancreatic stellate cell activa...

Xue(R),Zhou(J),Liu(Y),Wu(J),Song(X),Liu(Y)... Int J Biol Macromol 2026-02-00

...PIWIL1. Subsequently, PIWIL1 downregulates the expression of the rate-limiting polyamine metabolic enzymes ODC and SRM, ...

The Poly(rC) binding protein 2 is required for spermatogenesis by regulating ...

Xiong(Q),Qin(Z),Li(Y),Yim(WY),Wang(Z),Tan(... Int J Biol Macromol 2026-03-00

...Piwil1 and Dlec1), thereby orchestrating mRNA stability and alternative splicing of target genes. This study establishes...

Effects of 17β-estradiol interference on the temporal and spatial expression ...

Zhang(J),Ma(M),Li(S),Tian(T),Du(J),Lei(C),... Fish Physiol Biochem 2026-04-29

...piwil1 cDNA is 3091 bp in length and encodes a protein of 855 amino acids. qRT-PCR showed that piwil1 was highly express...

Noncanonical Transcription and Splicing Shape the Colorectal Cancer Immunopep...

Courcelles(M),Hardy(MP),Durette(C),Lanoix(... Mol Cell Proteomics 2026-06-00

...PIWIL1, L1TD1, and endogenous retroviral loci. Together, these data demonstrate that MSS CRC is not antigen poor and hig...

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