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PRMT3 in cancer: arginine methylation as a driver of tumor metabolism, immune...

Jin(H),Huang(H),Pan(X) Front Immunol None

...PRMT3 has more recently been implicated in several cancer-related processes. Accumulating evidence suggests that PRMT3 i...

PRMT3-Mediated Arginine Methylation Stabilizes PCSK9 to Promote Aortic Valve ...

Zhang(X),Hao(Y),Han(D),Jin(X),Shang(X),Zha... Circulation 2026-05-26

...Prmt3 haploinsufficiency were used to examine the role of PRMT3 in aortic valve calcification. The effects of PRMT3 inhi...

Protein arginine methyltransferase 3: Mechanism of action in diseases and mod...

Yu(D),He(K),Mai(C),Li(M) Bioorg Chem 2026-08-15

...PRMT3 modulators, including isoform-selective and partially isoform-selective PRMT3 inhibitors as well as PRMT3-targetin...

Computational insights into conformational dynamics and allosteric regulation...

Abbas(A),Miao(Z),Jin(J),Ye(F) Int J Biol Macromol 2026-04-00

...PRMT3 and PRMT6 suggests that selective modulation through regulatory sites outside the catalytic pocket may also be fea...

Arginine methyltransferase PRMT3 suppresses tumor-intrinsic immunity via prom...

Chen(Y),Liu(Y),Peng(J),Wang(X),Wei(Z),Yin(... Cancer Lett 2026-08-25

...PRMT3) exhibited a significantly negative association with antitumor immune signatures and survival outcomes in multiple...

PRMT3 Drives IDO1-Dependent Radioresistance and Immunosuppression by Promotin...

Zhang(S),Wang(S),Wang(Y),Zhou(T),Yang(J),X... Cancer Res 2026-01-16

...PRMT3) within tumors as a critical mediator impairing both radiotherapy sensitivity and T-cell antitumor activity. In tu...

PRMT3-mediated post-translational adaptation to fasting regulates metabolic f...

Huang(Z),Liu(X),Chen(X),Zhou(Y),Chen(Q),Li... Nat Commun 2026-02-02

...PRMT3 attenuates diet-induced obesity (DIO) and enhances adipocyte glycolysis in male mice. Mechanistically, PRMT3 drive...

A systematic review on age-related macular degeneration: New insights from mu...

Castro-Fernández(DC),Cañizo-Outeriño(A),Cu... Surv Ophthalmol None

...PRMT3. Additionally, this review revealed opportunities for personalized medicine in AMD patient stratification, improve...

Discovery of a first-in-class protein arginine methyltransferase 1 (PRMT1) de...

Ma(C),Sun(H),Shen(C),Li(X),Shen(Y) Eur J Med Chem 2025-07-05

...PRMT3/4/6), although it retains potent inhibitory effects on their enzymatic activity. Pharmacokinetics studies indicate...

PRMT3 at the crossroads of inflammation: dual roles in metabolic reprogrammin...

Hou(H),Meng(J),Chen(Y),Zhang(X),Yang(Z),Wa... Front Immunol None

...PRMT3 in inflammation-associated disorders. Mechanistically, PRMT3 aggravates inflammatory-metabolic dyshomeostasis in c...

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