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Targeting LY6E Inhibits Neuroblastoma Progression and Suppresses M2 Macrophage …

Li(L),Zeng(Y),Zhang(Q),Zhuang(G),Liu(Y),Wang… Hum Mutat None

...PTGDS) were utilized to construct a risk-scoring model that effectively stratified neuroblastoma patients into high- and...

Plasma exposome and proteome revealed the role of polycyclic aromatic hydrocarb…

Zhou(X),Deng(W),Chu(C),Wu(Q),Cao(Y),Chen(W),… Environ Int 2026-05-00

...PTGDS, DAG1, PEBP4, and YIPF3) with statistically significant interaction terms for the biphenyl-eGFR association. Combi...

Integrative analysis of single-cell and bulk RNA sequencing data using machine …

Wang(W),Niu(C),Zhao(C),Xu(Q),Guo(L),Liu(J),Z… J Mol Histol 2026-04-09

...PTGDS expression and OA risk. To validate the biological significance of PTGDS in SSF, a knee OA (KOA) rat model was est...

Integrating machine learning with SHAP to uncover multi-tissue molecular signat…

Zhao(J),Tao(J),Song(Y),Yang(J),Lin(X),Ye(Z),… PLoS One None

...PTGDS, CCL19, BGN, KLF9 (synovium); and GNL3L, C6orf111, NT5C3, ZNF148 (blood). Immune analysis indicated shifts in mast...

Downregulation of the L-PGDS/15d-PGJ2 Pathway Is Associated with Manganese-Indu…

Zhang(J),Xu(K),Ye(Y),Ma(J),Chen(L),Chen(T),N… Antioxidants (Basel) 2026-07-31

...Ptgds knockdown reduced endogenous 15d-PGJ2 production and increased MMP9 expression, whereas exogenous 15d-PGJ2 largely...

Targeting chitinase-3-like protein-1 in pancolitis by a drug-repurposing approa…

Bahramimehr(F),Kurz(S),Guthart(A),Krug(SM),F… Biochem Pharmacol 2026-07-27

...PTGDS, MMP3, CXCL1, and GREM1). We focused on CHI3L1 (chitinase-3-like protein-1) and confirmed its protein expression b...

Gestational NO₂ exposure induces anxiety- and depression-like behaviors in mice…

Li(W),Wang(X),Tang(S),Ye(S),Zeng(R),Zhang(R)… Neurotoxicology 2026-07-29

...PTGDS-PGD2 pathway were observed in both genders. We identified a hippocampal shift in tryptophan metabolism from seroto...

Macrophage Lipid Homeostasis Drives IVDD via a Senescence-Dependent Impairment …

Wang(J),Ling(S),Wang(Q),Qiao(X),Xing(J),Ji(S… Cell Prolif 2026-08-19

...PTGDS as lipid metabolism-related hub genes associated with IVDD. At the single-cell level, disc macrophages with low gl...

Chronic Intermittent Hypoxia Induces Hippocampal Cellular Remodeling through mi…

Ye(Y),Li(C),Huang(X),Sun(G),Zhang(Y),Rao(P),… Exp Neurol 2026-08-20

...Ptgds, S100a8, and S100a9. The intercellular communication network was extensively rewired, marked by strengthened micro...

ALB, GPX5 and PTGDS as potential biomarkers for the aging processes of the dog …

Cichowska-Likszo(AW),Likszo(P),Fraser(L),Mly… Reprod Fertil Dev 2026-01-30

...PTGDS, which could play roles in oxidative and ion metabolic regulation. These findings suggest that ALB, GPX5, and PTGD...

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