...RAG1-GFP(-) and RAG1-GFP(+) subpopulations. The RAG1-GFP(-) immature B-cell population was in the minority in C57BL/6(RA...
...RAG1-intrinsic mechanisms in determining RAG1 binding patterns is not known. Through analysis of deep RAG1 ChIP-seq data...
...RAG1 necessary for interaction with RAG2 and to measure the RAG1-RAG2 binding affinity (KD ∼0.4 μM) (where RAG1 and RAG2...
...RAG1 and RAG2 in signal recognition, we have compared the DNA binding activities of RAG1 alone and RAG1 plus RAG2 by gel...
...RAG1 by RAG2. Therefore, we propose that RAG2 coevolves with RAG1 to release inert RAG1 from aggregates and thereby acti...
RAG1 and RAG2 proteins are key components in V(D)J recombination. The core region of RAG1 is capable of catalyzing the r...
...RAG1 amino acids 218-263 upstream of the RAG1 ubiquitin ligase domain, but RAG1 was still able to undergo auto-ubiquityl...
...RAG1 promoter and suppression of RAG1 expression in primary ALL cells. Taken together, these results demonstrate that RA...
...RAG1 and RAG2 have been a focus of intense study for decades. To date, RAG1 has been studied as a single isoform; howeve...
...RAG1 in vivo, we generated core RAG1 knockin (RAG1(c/c)) mice. Significant B and T cell numbers are generated in RAG1(c/...
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