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SLC7A2-Mediated Lysine Catabolism Inhibits Immunosuppression in Triple Negative…

Sun(Y),Li(Y),Jiang(C),Liu(C),Song(Y) Crit Rev Eukaryot Gene Expr 2024-00-00

...SLC7A2 in TNBC. CD8A expression was detected using immunohistochemistry. We found that SLC7A2 is downregulated in TNBC t...

Lower SLC7A2 expression is associated with enhanced multidrug resistance, less …

Jiang(S),Zou(J),Dong(J),Shi(H),Chen(J),Li(Y)… Cell Commun Signal 2023-00-13

...SLC7A2 expression was down-regulated in NSCLC. Lower SLC7A2 expression was associated with worse recurrence-free surviva...

Pancreatic islet α cell function and proliferation require the arginine transpo…

Spears(E),Stanley(JE),Shou(M),Yin(L),Li(X),D… J Clin Invest 2026-06-15

...Slc7a2/SLC7A2 is the most highly expressed cationic amino acid transporter in α cells, with its expression being 3-fold ...

SLC7A2 deficiency promotes hepatocellular carcinoma progression by enhancing re…

Xia(S),Wu(J),Zhou(W),Zhang(M),Zhao(K),Liu(J)… Cell Death Dis 2021-00-02

...SLC7A2), a member of the solute carrier family, in HCC metastasis. The reduction of SLC7A2 was an independent and signif...

Loss of solute carrier family 7 member 2 exacerbates inflammation-associated co…

Coburn(LA),Singh(K),Asim(M),Barry(DP),Allama… Oncogene 2019-00-00

...SLC7A2 was localized predominantly to colonic epithelial cells in WT mice. Utilizing the AOM-DSS model, Slc7a2-/- mice h...

The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immuno…

Singh(Kshipra),Al-Greene(Nicole T),Verriere(… PLoS Pathog 0000-00-00

...SLC7A2. Mice lacking Slc7a2 exhibited reduced adherence of C. rodentium to the colonic epithelium and decreased expressi...

Pancreatic islet α cell function and proliferation requires the arginine transp…

Spears(E),Stanley(JE),Shou(M),Yin(L),Li(X),D… bioRxiv 2023-08-14

...Slc7a2ISLC7A2 is the most highly expressed cationic amino acid transporter in α cells with its expression being three-fo...

Targeting Purine Metabolism With 6-Mercaptopurine Overcomes Solute Carrier Fami…

Mao(YL),Mao(BY),Ouyang(YL),Zhang(Y),Cheng(P)… Oral Dis 2026-07-15

...SLC7A2 expression correlated with p53 signaling activity: SLC7A2 knockdown increased MDM2 expression and induced cisplat...

Bone Marrow Stem Cell Exosomes Protect Lung Cells from Oxygen Damage by Regulat…

He(Q),Zheng(H),Xiong(J),Yang(W) J Gene Med 2026-08-00

...Slc7a2 and overexpression and siRNA plasmids for miR-23a-3p and Slc7a2 were constructed. miR-23a-3p derived from BMSC ex...

Elevated SLC7A2 expression is associated with an abnormal neuroinflammatory res…

Gaudet(ID),Xu(H),Gordon(E),Cannestro(GA),Lu(… J Neuroinflammation 2024-02-28

...SLC7A2) as one of the top upregulated genes when normal Huntingtin was deleted. SLC7A2 has a high affinity for L-arginin...

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