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Circulating EV miRNA Cargo in Glioblastoma Patients Is Associated with Distin...

Popovic-Vukovic(M),Kolic(I),Stankovic(A),Z... Biomedicines 2026-03-18

...SOCS1, SOCS3, and PTEN, while CCND1 was downregulated. Correlation analyses suggested that certain EV miRNA changes para...

UV Light Inhibited HRV1b Replication but Reduced Adherens Epithelial Junction...

Maimuna(J),Yang(Z),Bachmann(E),Mittler(S),... Viruses 2026-02-28

...SOCS1, which is a negative regulator of IFN-β. Further, IR lights inhibited rhinovirus post infection in primary nasal e...

Ancient IL-6-STAT5 signaling orchestrates inflammation in jawless vertebrates...

Fontenla-Iglesias(F),Boulay(JL),Rast(JP),H... bioRxiv 2026-04-06

...SOCS1/3 genes, consistent with an IL-6/STAT5/SOCS regulatory axis. These findings extend the repertoire of immune-relate...

Hijacking innate immunity to enhance mRNA therapeutics by blocking IFN-P-body...

Zhang(T),Peng(X),Qin(J),Zhu(B),Zhang(S),De... Nat Commun 2026-04-17

...SOCS1 and the coronaviral membrane protein (M) emerging as the most potent. Multi-omics analyses reveal that pseudouridi...

USP13 stabilizes SOCS1 to reverse αPD-1 resistance in MSI-H colorectal cancer...

Zheng(Z),Ni(Y),Wu(M),Ding(L),Li(H),Zhang(N... Oncogene 2026-06-00

...SOCS1, increased SOCS1 protein stability, and mediated K63-linked deubiquitination of SOCS1. Collectively, these finding...

Pluripotency Factors Modulate Interferon Signaling in Embryonic Stem Cells.

Yang(Q),Padilla-Galvez(M),Uhl(S),Eggenberg... bioRxiv 2026-03-27

...SOCS1 and SPRY4. Depletion of SOCS1 enabled hESCs to respond robustly to interferon stimulation, showing that this negat...

The LINC00612/miR-331-3p/SOCS1 axis mediates the cardioprotective effect of s...

Lin(Y),Liu(J),Ou(G) Arch Biochem Biophys 2026-07-00

...SOCS1 axis. AC16 cells were used to establish an H/R model to simulate MIRI, with pretreatment by Sev. RT-qPCR was used ...

An in vivo CRISPR screen unveils promising target genes to improve CAR-T cell...

Fumagalli(M),An(D),Simula(L),Combe(C),Azie... Mol Ther 2026-07-01

...SOCS1, PTPN2, and CDKN2A as the most robust targets to improve persistence of EGFR CAR-T cells in human lung tumor-beari...

SOCS1-based therapeutic peptides improve liver disease and metabolic dysfunct...

Soto-Catalán(M),Opazo-Ríos(L),Espadas(C),R... Sci Rep 2026-04-09

...SOCS1-derived peptidomimetic (MiS1) in a mouse model of MASLD using obese, type 2 diabetic BTBR ob/ob mice. A six-week t...

Evolving therapeutic pipeline for tumor-infiltrating lymphocytes in metastati...

Wu(JF),Abid(MA),Singh(SP),Mohlere(V),Abid(MB) Front Immunol None

...SOCS1, while KSQ-004EX additionally targets Regnase-1 to enhance TIL function. Emerging strategies including IL-2-indepe...

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