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SOX12 and DELTA mediate ecdysone-driven adult neural cell proliferation during …

Wang(L),Liang(LQ),Feng(PY),Li(Y),Wang(JX),Zh… J Biol Chem 2026-08-07

...SOX12 and DELTA via nuclear receptor EcRA. SOX12 exhibits significantly elevated expression and is localized in the brai...

The SoxC transcription factors regulate multiple early retinal lineages and fun…

Enriquez(S),Ge(Y),Nan(N),Lefebvre(V),Liu(T),… bioRxiv 2026-07-27

...Sox12) are also involved in RGC genesis, but their precise integration into the Atoh7-driven regulatory hierarchy remain...

The mutual regulation of SOX12 and RNF168 modulates cisplatin resistance in eso…

Wang(N),Yang(L),Huang(Y),Wang(Y),Liu(M),Yang… Cell Biosci 2026-01-19

...SOX12 plays a role in cisplatin resistance in hepatocellular carcinoma cells, but the function and mechanism of SOX12 in...

CITED2 deficiency drives pulmonary hypoplasia via miR-200b and inflammatory pat…

Jank(M),Kuna(M),Wang(J),Schwartz(J),Miyake(Y… J Pediatr Surg 2026-06-00

...Sox12 downregulated in a rat nitrofen model of CDH, but Sox4 and Sox11 upregulated in CITED2-deficient rats. CITED2 defi...

The oncogenic potential of SOX12: a comprehensive and perspective view.

Leng(H),Liu(Y),Wu(L) J Transl Med 2026-06-15

Sex-determining region Y-box 12 (SOX12), a key member of the SOXC transcription factor subfamily, exerts oncogenic roles...

SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Emb…

Kato(Kenji),Bhattaram(Pallavi),Penzo-Méndez(… J Bone Miner Res 2016-06-20

...SOX12 transcription factors, in growth plates. We show that the three genes are expressed robustly in perichondrocytes a...

Sox transcription factors require selective interactions with Oct4 and specific…

Aksoy(Irene),Jauch(Ralf),Eras(Volker),Chng(W… Stem Cells 2015-01-15

...Sox12, Sox13, and Sox18 cannot. Next we studied regions outside the HMG domain and found that the C-terminal transactiva...

Sox12, a direct target of FoxQ1, promotes hepatocellular carcinoma metastasis t…

Huang(Wenjie),Chen(Zhangqian),Shang(Xin),Tia… Hepatology 2015-08-04

...Sox12/Twist1, Sox12/FGFBP1, or FoxQ1/Sox12 were associated with poorer prognosis.,Up-regulated Sox12 induced by FoxQ1 pr...

A novel genome-wide in vivo screen for metastatic suppressors in human colon ca…

Duquet(Arnaud),Melotti(Alice),Mishra(Sonaksh… EMBO Mol Med 2015-02-09

...SOX12, the knockdown of which increases metastatic growth after direct seeding. Moreover, both modify the type of self-r...

SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates i…

Bhattaram(Pallavi),Penzo-Méndez(Alfredo),Kat… J Cell Biol 2015-03-03

...Sox12, are coexpressed in skeletogenic mesenchyme, including presumptive joints and perichondrium, but not in cartilage....

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