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IL5RA

Gene name:interleukin 5 receptor subunit alpha

...IL5RA通过与IL-5结合激活JAK-STAT、MAPK和PI3K等信号通路,调控下游基因表达。该基因突变可能导致受体功能异常,与嗜酸性粒细胞增多症、哮喘、慢性鼻窦炎伴鼻息肉(CRSwNP)等过敏性和炎症性疾病密切相关。例如,某些IL5R...

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