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MIR7-3

Gene name:microRNA 7-3

...MIR7-3表达下调,与神经退行性疾病(如帕金森病)和多种癌症(如胶质瘤、乳腺癌)的发生相关,因其失去对异常信号通路的抑制作用。过表达MIR7-3可增强肿瘤抑制效果,但可能干扰正常发育所需的信号传导;而表达降低则促进细胞恶性转化。此外,MI...

MIR7-3HG

Gene name:MIR7-3 host gene

MIR7-3HG(MicroRNA 7-3 Host Gene)是一个长链非编码RNA(lncRNA)基因,位于人类染色体19q13.33上。它作为miR-7的前体基因,通过转录加工产生成熟的miR-7 microRNA,后者在多种生物学过...

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