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PMID: 10748864 Published · ppublish English Journal Article Review

The Epstein-Barr virus and its association with human cancers.

Molecular pathology : MP ·Vol. 52 ·No. 6 ·1999-12-00 ·Pages 307-22

Baumforth KR, Young LS, Flavell KJ, Constandinou C, Murray PG

Abstract

The Epstein-Barr virus (EBV) has been linked to the development of a variety of human malignancies, including Burkitt's lymphoma, Hodgkin's disease, nasopharyngeal carcinoma, some T cell lymphomas, post-transplant lymphoproliferative disease, and more recently, certain cancers of the stomach and smooth muscle. This review summarizes these associations and in particular the role of the viral latent genes in the transformation process.

MeSH Terms
Cell Transformation, Neoplastic Cell Transformation, Viral Epstein-Barr Virus Infections/complications Herpesvirus 4, Human/physiology Humans Lymphoma/virology Neoplasms/virology Virus Latency/genetics
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Baumforth K R
Biomedical Research Laboratories, School of Health Sciences, University of Wolverhampton, UK.
Young L S
Flavell K J
Constandinou C
Murray P G
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Article Info
Journal
Molecular pathology : MP
Abbr.
Mol Pathol
ISSN
1366-8714
DOI
10.1136/mp.52.6.307
Published
1999-12-00
Pages
307-22
Language
English
Region
England
NLM ID
9706282
PMCID
PMC395716
Subset
IM
External Links
PubMed source DOI: 10.1136/mp.52.6.307 PMC Full Text
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