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PMID: 11102381 Published · ppublish English Comparative Study Journal Article

Molecular population genetics of male accessory gland proteins in Drosophila.

Genetics ·Vol. 156 ·No. 4 ·2000-12-00 ·Pages 1879-88

Begun DJ, Whitley P, Todd BL, Waldrip-Dail HM, Clark AG

Abstract

Drosophila seminal proteins have an unusually high rate of molecular sequence evolution, suggesting either a high rate of neutral substitution or rapid adaptive evolution. To further quantify patterns of polymorphism and divergence in genes encoding seminal proteins, also called accessory gland proteins (Acp's), we conducted a sequencing survey of 10 Acp genes in samples of Drosophila melanogaster and D. simulans (Acp29AB, Acp32CD, Acp33A, Acp36DE, Acp53Ea, Acp62F, Acp63F, Acp76A, Acp95EF, and Acp98AB). Mean heterozygosity at replacement sites in D. simulans was 0.0074 for Acp genes and 0.0013 for a set of 19 non-Acp genes, and mean melanogaster-simulans divergence at replacement sites was 0.0497 for Acp genes and 0.0107 at non-Acp genes. The elevated divergence of Acp genes is thus accompanied by elevated within-species polymorphism. In addition to the already-reported departures of Acp26A, Acp29AB, and Acp70A from neutrality, our data reject neutrality at Acp29AB and Acp36DE in the direction of excess replacements in interspecific comparisons.

MeSH Terms
Animals California Drosophila/genetics,metabolism Drosophila melanogaster/genetics Evolution, Molecular Female Genes, Insect Genetics, Population Genitalia, Male/metabolism Insect Proteins/genetics Male Polymorphism, Genetic Semen/metabolism Spain Species Specificity Zimbabwe
Chemicals
Insect Proteins
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Begun D J
Section of Integrative Biology and Institute for Cellular and Molecular Biology, University of Texas, Austin, Texas 78712, USA. [email protected]
Whitley P
Todd B L
Waldrip-Dail H M
Clark A G
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/156.4.1879
Email
[email protected]
Published
2000-12-00
Pages
1879-88
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1461396
Subset
IM
External Links
PubMed source DOI: 10.1093/genetics/156.4.1879 PMC Full Text View journal details
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