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PMID: 15608215 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

CandidaDB: a genome database for Candida albicans pathogenomics.

Nucleic acids research ·Vol. 33 ·No. Database issue ·2005-01-01 ·Pages D353-7

d'Enfert C, Goyard S, Rodriguez-Arnaveilhe S, Frangeul L, Jones L, Tekaia F, Bader O, Albrecht A, Castillo L, Dominguez A, Ernst JF, Fradin C, Gaillardin C, Garcia-Sanchez S, de Groot P, Hube B, Klis FM, Krishnamurthy S, Kunze D, Lopez MC, Mavor A, Martin N, Moszer I, Onésime D, Perez Martin J, Sentandreu R, Valentin E, Brown AJ

Abstract

CandidaDB is a database dedicated to the genome of the most prevalent systemic fungal pathogen of humans, Candida albicans. CandidaDB is based on an annotation of the Stanford Genome Technology Center C.albicans genome sequence data by the European Galar Fungail Consortium. CandidaDB Release 2.0 (June 2004) contains information pertaining to Assembly 19 of the genome of C.albicans strain SC5314. The current release contains 6244 annotated entries corresponding to 130 tRNA genes and 5917 protein-coding genes. For these, it provides tentative functional assignments along with numerous pre-run analyses that can assist the researcher in the evaluation of gene function for the purpose of specific or large-scale analysis. CandidaDB is based on GenoList, a generic relational data schema and a World Wide Web interface that has been adapted to the handling of eukaryotic genomes. The interface allows users to browse easily through genome data and retrieve information. CandidaDB also provides more elaborate tools, such as pattern searching, that are tightly connected to the overall browsing system. As the C.albicans genome is diploid and still incompletely assembled, CandidaDB provides tools to browse the genome by individual supercontigs and to examine information about allelic sequences obtained from complementary contigs. CandidaDB is accessible at http://genolist.pasteur.fr/CandidaDB.

MeSH Terms
Candida albicans/genetics,pathogenicity Databases, Genetic Fungal Proteins/chemistry,genetics,physiology Genome, Fungal Genomics Internet User-Computer Interface
Chemicals
Fungal Proteins
Authors & Affiliations
28 authors, click to expand affiliations / ORCID
d'Enfert C
Unité Postulante Biologie et Pathogénicité Fongiques, INRA USC 2019, Institut Pasteur, Paris, France. [email protected]
Goyard S
Rodriguez-Arnaveilhe S
Frangeul L
Jones L
Tekaia F
Bader O
Albrecht Antje
Castillo L
Dominguez A
Ernst J F
Fradin C
Gaillardin C
Garcia-Sanchez S
de Groot P
Hube B
Klis F M
Krishnamurthy S
Kunze D
Lopez M-C
Mavor A
Martin N
Moszer I
Onésime D
Perez Martin J
Sentandreu R
Valentin E
Brown A J P
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gki124
Email
[email protected]
Published
2005-01-01
Pages
D353-7
Language
English
Region
England
NLM ID
0411011
PMCID
PMC540078
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/gki124 PMC Full Text View journal details
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