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PMID: 15608235 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Ensembl 2005.

Nucleic acids research ·Vol. 33 ·No. Database issue ·2005-01-01 ·Pages D447-53

Hubbard T, Andrews D, Caccamo M, Cameron G, Chen Y, Clamp M, Clarke L, Coates G, Cox T, Cunningham F, Curwen V, Cutts T, Down T, Durbin R, Fernandez-Suarez XM, Gilbert J, Hammond M, Herrero J, Hotz H, Howe K, Iyer V, Jekosch K, Kahari A, Kasprzyk A, Keefe D, Keenan S, Kokocinsci F, London D, Longden I, McVicker G, Melsopp C, Meidl P, Potter S, Proctor G, Rae M, Rios D, Schuster M, Searle S, Severin J, Slater G, Smedley D, Smith J, Spooner W, Stabenau A, Stalker J, Storey R, Trevanion S, Ureta-Vidal A, Vogel J, White S, Woodwark C, Birney E

Abstract

The Ensembl (http://www.ensembl.org/) project provides a comprehensive and integrated source of annotation of large genome sequences. Over the last year the number of genomes available from the Ensembl site has increased by 7 to 16, with the addition of the six vertebrate genomes of chimpanzee, dog, cow, chicken, tetraodon and frog and the insect genome of honeybee. The majority have been annotated automatically using the Ensembl gene build system, showing its flexibility to reliably annotate a wide variety of genomes. With the increased number of vertebrate genomes, the comparative analysis provided to users has been greatly improved, with new website interfaces allowing annotation of different genomes to be directly compared. The Ensembl software system is being increasingly widely reused in different projects showing the benefits of a completely open approach to software development and distribution.

MeSH Terms

Animals Base Sequence Cattle Databases, Nucleic Acid Dogs Genomics Humans Internet Mice Rats Sequence Alignment Software User-Computer Interface

Authors & Affiliations

52 authors, click to expand affiliations / ORCID

Hubbard T

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.

Andrews D

Caccamo M

Cameron G

Chen Y

Clamp M

Clarke L

Coates G

Cox T

Cunningham F

Curwen V

Cutts T

Down T

Durbin R

Fernandez-Suarez X M

Gilbert J

Hammond M

Herrero J

Hotz H

Howe K

Iyer V

Jekosch K

Kahari A

Kasprzyk A

Keefe D

Keenan S

Kokocinsci F

London D

Longden I

McVicker G

Melsopp C

Meidl P

Potter S

Proctor G

Rae M

Rios D

Schuster M

Searle S

Severin J

Slater G

Smedley D

Smith J

Spooner W

Stabenau A

Stalker J

Storey R

Trevanion S

Ureta-Vidal A

Vogel J

White S

Woodwark C

Birney E

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

1362-4962

DOI

10.1093/nar/gki138

Published

2005-01-01

Pages

D447-53

Language

English

Region

England

NLM ID

0411011

PMCID

PMC540092

Subset

External Links

PubMed source DOI: 10.1093/nar/gki138 PMC Full Text View journal details

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Ensembl 2005.

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