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PMID: 1670938 Published · ppublish English Journal Article

Nucleotide sequence and functions of mrk determinants necessary for expression of type 3 fimbriae in Klebsiella pneumoniae.

Journal of bacteriology ·Vol. 173 ·No. 2 ·1991-01-00 ·Pages 916-20

Allen BL, Gerlach GF, Clegg S

Abstract

The nucleotide sequence of six genes involved in the expression of type 3 fimbriae of Klebsiella pneumoniae was determined. In addition to the genes that encode the fimbrial subunit (mrkA) and adhesion (mrkD), the mrkB, mrkC, and mrkE genes appear to be involved in assembly of the fimbrial filament and regulation of type 3 fimbrial expression. The mrkF gene product is required to maintain the stability of the fimbrial filament on the cell surface.

Related Genes
mrk
MeSH Terms
Adhesins, Bacterial Amino Acid Sequence Bacterial Adhesion Bacterial Proteins/genetics Base Sequence Fimbriae Proteins Fimbriae, Bacterial/physiology Genes, Bacterial Klebsiella pneumoniae/genetics Molecular Sequence Data Multigene Family Open Reading Frames Plasmids
Chemicals
Adhesins, Bacterial Bacterial Proteins Klebsiella pneumoniae type 3 fimbrial adhesin Fimbriae Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Allen B L
Department of Microbiology, University of Iowa, Iowa City 52242.
Gerlach G F
Clegg S
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19 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.173.2.916-920.1991
Published
1991-01-00
Pages
916-20
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC207091
Subset
IM
Databases
GENBANK
M55511, M55912, M63255, M63306, M64332, S69596, S69601, S69604, S69828, S69830
External Links
PubMed source DOI: 10.1128/jb.173.2.916-920.1991 PMC Full Text View journal details
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