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PMID: 1713189 Published · ppublish English Comment Journal Article

Do we need a pepton hypothesis?

Immunogenetics ·Vol. 34 ·No. 1 ·1991-00-00 ·Pages 1-4

Lindahl KF

Abstract

暂无摘要

Related Genes
neo<up>r</up>
MeSH Terms
Animals Antigens, Neoplasm/biosynthesis Gene Expression Regulation Histocompatibility Antigens/biosynthesis Immune Tolerance Models, Genetic RNA/metabolism T-Lymphocytes/immunology Transcription, Genetic
Chemicals
Antigens, Neoplasm Histocompatibility Antigens tumor-associated transplantation antigen RNA
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Lindahl K F
Howard Hughes Medical Institute, Department of Microbiology, University of Texas Southwestern Medical Center, Dallas 75235-9050.
References (46)
46 references, click to expand
  1. Simian virus 40 (SV40)-transgenic mice that develop tumors are specifically tolerant to SV40 T antigen.
    J Exp Med. 1987 Feb 1;165(2):417-27 PMID: 3029269
  2. The expression of influenza virus hemagglutinin in the pancreatic beta cells of transgenic mice results in autoimmune diabetes.
    Cell. 1990 May 4;61(3):383-96 PMID: 2185889
  3. Identification of classical minor histocompatibility antigen as cell-derived peptide.
    Nature. 1990 Jan 18;343(6255):275-8 PMID: 1689009
  4. Maternally transmitted antigen of mice: a model transplantation antigen.
    Annu Rev Immunol. 1991;9:351-72 PMID: 1910682
  5. Limit of T cell tolerance to self proteins by peptide presentation.
    Science. 1990 Mar 30;247(4950):1587-9 PMID: 2321019
  6. A 15 amino acid fragment of influenza nucleoprotein synthesized in the cytoplasm is presented to class I-restricted cytotoxic T lymphocytes.
    J Exp Med. 1989 Sep 1;170(3):1051-6 PMID: 2475569
  7. Peripheral tolerance mechanisms prevent the development of autoreactive T cells in chimeras grafted with two minor incompatible thymuses.
    Eur J Immunol. 1989 Jan;19(1):111-7 PMID: 2522046
  8. Structure of the gene of tum- transplantation antigen P198: a point mutation generates a new antigenic peptide.
    J Exp Med. 1990 Jul 1;172(1):35-45 PMID: 1694221
  9. The binary logic of antigen processing and presentation to T cells.
    Cell. 1990 Jul 27;62(2):203-6 PMID: 1695549
  10. Genes coding for T-cell-defined tum transplantation antigens: point mutations, antigenic peptides, and subgenic expression.
    Cold Spring Harb Symp Quant Biol. 1989;54 Pt 1:587-96 PMID: 2700947
  11. Specificity of peptide binding by the HLA-A2.1 molecule.
    J Immunol. 1989 Nov 1;143(9):2939-47 PMID: 2553813
  12. H-40, an antigen controlled by an Igh linked gene and recognized by cytotoxic T lymphocytes. I. Genetic analysis of H-40 and distribution of its product on B cell tumors.
    J Exp Med. 1984 Jun 1;159(6):1724-40 PMID: 6427384
  13. Structure of the gene of tum- transplantation antigen P35B: presence of a point mutation in the antigenic allele.
    EMBO J. 1990 Apr;9(4):1041-50 PMID: 2108859
  14. Association of class I major histocompatibility heavy and light chains induced by viral peptides.
    Nature. 1989 Aug 10;340(6233):443-8 PMID: 2666863
  15. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides.
    Cell. 1986 Mar 28;44(6):959-68 PMID: 2420472
  16. Nuclear myxovirus-resistance protein Mx is a minor histocompatibility antigen.
    Proc Natl Acad Sci U S A. 1990 Mar;87(5):2021-5 PMID: 2308961
  17. Tumor-specific T-cell clones recognize different protein determinants of autologous human malignant melanoma cells.
    Int J Cancer. 1990 May 15;45(5):834-41 PMID: 2159436
  18. T cell-recognized antigenic peptides derived from the cellular genome are not protein degradation products but can be generated directly by transcription and translation of short subgenic regions. A hypothesis.
    Immunogenetics. 1989;29(2):75-9 PMID: 2783681
  19. Assembly of MHC class I molecules analyzed in vitro.
    Cell. 1990 Jul 27;62(2):285-95 PMID: 2196996
  20. Protein-specific cytotoxic T lymphocytes. Recognition of transfectants expressing intracellular, membrane-associated or secreted forms of beta-galactosidase.
    Immunogenetics. 1989;30(4):296-302 PMID: 2507447
  21. Presentation of viral antigen controlled by a gene in the major histocompatibility complex.
    Nature. 1990 May 31;345(6274):449-52 PMID: 2342577
  22. SV40 T-antigen is a histocompatibility antigen of SV40-transgenic mice.
    Immunogenetics. 1988;27(6):436-41 PMID: 2836306
  23. Elevated recombination rates in transcriptionally active DNA.
    Cell. 1989 Feb 24;56(4):619-30 PMID: 2645056
  24. SV40 T antigen acts as a minor histocompatibility antigen of SV40 T antigen tolerant transgenic mice.
    Immunogenetics. 1989;29(6):366-70 PMID: 2786497
  25. Access to a messenger RNA sequence or its protein product is not limited by tissue or species specificity.
    Science. 1989 Apr 21;244(4902):331-4 PMID: 2565599
  26. The pepton hypothesis and autoimmunity.
    Immunogenetics. 1990;31(1):61-2 PMID: 1688824
  27. Genetic and physical linkage of exogenous sequences in transformed cells.
    Cell. 1980 Nov;22(1 Pt 1):309-17 PMID: 6253083
  28. Recombinant fragment assay for gene targetting based on the polymerase chain reaction.
    Nucleic Acids Res. 1988 Sep 26;16(18):8887-903 PMID: 3174435
  29. Introduction of soluble protein into the class I pathway of antigen processing and presentation.
    Cell. 1988 Sep 9;54(6):777-85 PMID: 3261634
  30. Influenza-specific cytotoxic T-cell recognition is inhibited by peptides unrelated in both sequence and MHC restriction.
    Immunology. 1989 Feb;66(2):163-9 PMID: 2466767
  31. Tolerance of class I histocompatibility antigens expressed extrathymically.
    Nature. 1989 Jun 22;339(6226):622-4 PMID: 2786608
  32. Structure of the gene of tum- transplantation antigen P91A: the mutated exon encodes a peptide recognized with Ld by cytolytic T cells.
    Cell. 1989 Jul 28;58(2):293-303 PMID: 2568889
  33. Cellular peptide composition governed by major histocompatibility complex class I molecules.
    Nature. 1990 Nov 15;348(6298):248-51 PMID: 2234092
  34. Class I MHC can present an endogenous peptide to cytotoxic T lymphocytes.
    J Exp Med. 1989 Sep 1;170(3):1033-8 PMID: 2475568
  35. Competitor analogs for defined T cell antigens: peptides incorporating a putative binding motif and polyproline or polyglycine spacers.
    Cell. 1990 Jan 12;60(1):63-72 PMID: 2295089
  36. Expression in transgenic mice of class I histocompatibility antigens controlled by the metallothionein promoter.
    Proc Natl Acad Sci U S A. 1989 May;86(10):3782-6 PMID: 2657728
  37. Tissue-specific and tissue-restricted histocompatibility antigens.
    Immunol Today. 1984 Aug;5(8):234-40 PMID: 25290145
  38. Characterization of naturally occurring minor histocompatibility peptides including H-4 and H-Y.
    Science. 1990 Jul 20;249(4966):283-7 PMID: 1695760
  39. Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes.
    Nature. 1989 Oct 26;341(6244):749-52 PMID: 2477713
  40. T-lymphocyte recognition of a membrane glycoprotein.
    Cold Spring Harb Symp Quant Biol. 1989;54 Pt 1:477-85 PMID: 2639766
  41. Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I.
    Cell. 1987 Mar 27;48(6):1071-9 PMID: 3548996
  42. Extrathymic acquisition of tolerance by T lymphocytes.
    Cold Spring Harb Symp Quant Biol. 1989;54 Pt 2:807-13 PMID: 2701217
  43. Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein.
    Cell. 1990 Mar 23;60(6):971-80 PMID: 2317868
  44. Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes.
    Nature. 1985 May 9-15;315(6015):115-22 PMID: 2986015
  45. Recombination between immunoglobulin variable region gene segments is enhanced by transcription.
    Nature. 1986 Dec 11-17;324(6097):585-9 PMID: 3491327
  46. Specialized functions of MHC class I molecules. I. An N-formyl peptide receptor is required for construction of the class I antigen Mta.
    J Exp Med. 1990 Mar 1;171(3):897-912 PMID: 2307936
Article Info
Journal
Immunogenetics
Abbr.
Immunogenetics
ISSN
0093-7711
DOI
10.1007/BF00212305
Published
1991-00-00
Pages
1-4
Language
English
Region
United States
NLM ID
0420404
Subset
IM
Corrections
CommentOn
PMID: 2783681
External Links
PubMed source DOI: 10.1007/BF00212305 View journal details
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