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PMID: 17870621 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

In praise of tedious anatomy.

NeuroImage ·Vol. 37 ·No. 4 ·2007-10-01 ·Pages 1033-41; discussion 1050-8

Devlin JT, Poldrack RA

Abstract

Functional neuroimaging is fundamentally a tool for mapping function to structure, and its success consequently requires neuroanatomical precision and accuracy. Here we review the various means by which functional activation can be localised to neuroanatomy and suggest that the gold standard should be localisation to the individual's or group's own anatomy through the use of neuroanatomical knowledge and atlases of neuroanatomy. While automated means of localisation may be useful, they cannot provide the necessary accuracy, given variability between individuals. We also suggest that the field of functional neuroimaging needs to converge on a common set of methods for reporting functional localisation including a common "standard" space and criteria for what constitutes sufficient evidence to report activation in terms of Brodmann's areas.

MeSH Terms
Anatomy/trends Atlases as Topic Humans Magnetic Resonance Imaging Nervous System/anatomy & histology,ultrastructure Nervous System Physiological Phenomena Neural Pathways/anatomy & histology
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Devlin Joseph T
Centre for Functional Magnetic Resonance of the Brain, University of Oxford, UK. [email protected]
Poldrack Russell A
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Article Info
Journal
NeuroImage
Abbr.
Neuroimage
ISSN
1053-8119
DOI
10.1016/j.neuroimage.2006.09.055
Email
[email protected]
Published
2007-10-01
Pages
1033-41; discussion 1050-8
Language
English
Region
United States
NLM ID
9215515
PMCID
PMC1986635
Subset
IM
Grants
Wellcome Trust · United Kingdom
Wellcome Trust · 075481 · United Kingdom
NCRR NIH HHS · P20 RR020750 · United States
Corrections
CommentIn
PMID: 17428686
CommentIn
PMID: 17560127
CommentIn
PMID: 17719800
CommentIn
PMID: 17720552
CommentIn
PMID: 17766148
CommentIn
PMID: 17822924
CommentIn
PMID: 17870622
External Links
PubMed source DOI: 10.1016/j.neuroimage.2006.09.055 PMC Full Text View journal details
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