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PMID: 20064446 Published · ppublish English Journal Article Review

Diversity in T cell memory: an embarrassment of riches.

Immunity ·Vol. 31 ·No. 6 ·2009-12-18 ·Pages 859-71

Jameson SC, Masopust D

Abstract

The adaptive immune response meets the needs of the organism to generate effector cells capable of controlling pathogens but also leads to production of memory cells, which mediate more effective protection during rechallenge. In this review, we focus on the generation, maintenance, and function of memory T cells, with a special emphasis on the increasing evidence for great diversity among functional memory T cell subsets.

MeSH Terms
Adaptive Immunity Animals Apoptosis/immunology Cell Differentiation/immunology Cytokines/immunology,metabolism Homeostasis/immunology Humans Immunity, Innate Immunologic Memory Infections/immunology Inflammation/immunology,metabolism T-Lymphocyte Subsets/immunology,metabolism
Chemicals
Cytokines
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Jameson Stephen C
Department of Laboratory Medicine and Pathology and Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA. [email protected]
Masopust David
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Article Info
Journal
Immunity
Abbr.
Immunity
ISSN
1097-4180
DOI
10.1016/j.immuni.2009.11.007
Email
[email protected]
Published
2009-12-18
Pages
859-71
Language
English
Region
United States
NLM ID
9432918
PMCID
PMC2957815
Subset
IM
Grants
NIAID NIH HHS · R01 AI075168 · United States
NIAID NIH HHS · R01 AI075168-04 · United States
External Links
PubMed source DOI: 10.1016/j.immuni.2009.11.007 PMC Full Text View journal details
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