The complete nucleotide sequence of the Escherichia coli gene appA reveals significant homology between pH 2.5 acid phosphatase and glucose-1-phosphatase.

Journal of bacteriology ·Vol. 172 ·No. 9 ·1990-09-00 ·Pages 5497-500

Dassa J, Marck C, Boquet PL

Abstract

The whole nucleotide sequence of Escherichia coli gene appA, which encodes periplasmic phosphoanhydride phosphohydrolase (optimum pH, 2.5), and its flanking regions was determined. The AppA protein is significantly homologous to the product of the nearby gene agp, acid glucose-1-phosphatase. Because identical amino acids are distributed over the whole lengths of the proteins, it is likely that appA and agp originate from the same ancestor gene.

MeSH Terms

Acid Phosphatase/genetics Amino Acid Sequence Base Sequence Escherichia coli/enzymology,genetics Escherichia coli Proteins Genes, Bacterial Hydrogen-Ion Concentration Molecular Sequence Data Phosphoric Monoester Hydrolases/genetics Restriction Mapping Sequence Homology, Nucleic Acid

Chemicals

Escherichia coli Proteins agp protein, E coli Acid Phosphatase Phosphoric Monoester Hydrolases

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Dassa J

Service de Biochimie, Département de Biologie, Gif-sur-Yvette, France.

Marck C

Boquet P L

References (17)

17 references, click to expand

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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.172.9.5497-5500.1990

Published

1990-09-00

Pages

5497-500

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC213220

Subset

Databases

GENBANK

M58708

External Links

PubMed source DOI: 10.1128/jb.172.9.5497-5500.1990 PMC Full Text View journal details

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The complete nucleotide sequence of the Escherichia coli gene appA reveals significant homology between pH 2.5 acid phosphatase and glucose-1-phosphatase.

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