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PMID: 2326191 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Information content of Caenorhabditis elegans splice site sequences varies with intron length.

Nucleic acids research ·Vol. 18 ·No. 6 ·1990-03-25 ·Pages 1509-12

Fields C

Abstract

A database of sequences of 139 introns from the nematode Caenorhabditis elegans was analyzed using the information measure of Schneider et al. (1986) J. Mol. Biol. 128: 415-431. Statistically significant information is encoded by at least the first 30 nt and last 20 nt of C. elegans introns. Both the quantity and the distribution of information in the 5' splice site sequences differs between the typical short (length less than 75 nt) and rarer long (length greater than 75 nt) introns, with the 5 sites of long introns containing approximately one bit more information. 3' splice site sequences of long and short C. elegans introns differ significantly in the region between -20 and -10 nt.

MeSH Terms
Animals Base Sequence Caenorhabditis/genetics Information Systems Introns Molecular Sequence Data RNA Splicing
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Fields C
Center for Advanced Computing in Molecular and Cellular Biology, New Mexico State University, Las Cruces 88003-0001.
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/18.6.1509
Published
1990-03-25
Pages
1509-12
Language
English
Region
England
NLM ID
0411011
PMCID
PMC330518
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/18.6.1509 PMC Full Text View journal details
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