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PMID: 24177791 Published · ppublish English Journal Article

Suppressible alleles in a wide domain regulatory gene in Aspergillus nidulans.

Current genetics ·Vol. 8 ·No. 4 ·1984-05-00 ·Pages 245-51

Al Taho NM, Sealy-Lewis HM, Scazzocchio C

Abstract

The areA gene of Aspergillus nidulans is a one of the better studied eukaryotic wide domain regulatory genes, necessary for the expression of most structural genes involved in the utilization of a wide variety of nitrogen sources (Arst and Cove 1973; Arst 1983). Here we report the isolation and properties of areA alleles suppressible by translational suppressors (Roberts et al. 1979). Thus we show formally that the areA gene specifies a protein rather than an RNA product and we show that it is possible to generate by external suppression areA gene products with modified properties.

Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Al Taho N M
Department of Biology, University of Essex, Wivenhoe Park, Colchester, C04 3SQ, Essex, England.
Sealy-Lewis H M
Scazzocchio C
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Article Info
Journal
Current genetics
Abbr.
Curr Genet
ISSN
0172-8083
DOI
10.1007/BF00419720
Published
1984-05-00
Pages
245-51
Language
English
Region
United States
NLM ID
8004904
External Links
PubMed source DOI: 10.1007/BF00419720 View journal details
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