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PMID: 2471510 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Unconventional codon reading by Mycoplasma mycoides tRNAs as revealed by partial sequence analysis.

The Biochemical journal ·Vol. 258 ·No. 3 ·1989-03-15 ·Pages 869-73

Guindy YS, Samuelsson T, Johansen TI

Abstract

Continuing our investigation of the tRNA genes and gene products in Mycoplasma mycoides, we report the sequence of the gene for tRNALeu (CAA) as well as partial primary structures of the following tRNAs: Leu (CAA), Leu (UAG), Arg (UCU), Thr (AGU) and Ile (CAU). It is suggested that in M. mycoides, at least some of the family codon boxes are read by only one tRNA each, using an unconventional method which does not discriminate between the nucleotides in the third codon position. M. mycoides is the first free-living organism known to use an unconventional method of this kind.

MeSH Terms
Base Sequence Cloning, Molecular Codon Genes, Bacterial Molecular Sequence Data Mycoplasma mycoides/genetics RNA, Bacterial/genetics RNA, Messenger RNA, Transfer/genetics
Chemicals
Codon RNA, Bacterial RNA, Messenger RNA, Transfer
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Guindy Y S
Department of Medical Biochemistry, University of Göteborg, Sweden.
Samuelsson T
Johansen T I
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19 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj2580869
Published
1989-03-15
Pages
869-73
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1138444
Subset
IM
External Links
PubMed source DOI: 10.1042/bj2580869 PMC Full Text View journal details
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