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An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2.
Nature. 1987 Oct 29-Nov 4;329(6142):840-2
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Defective natural killer cytotoxicity and polymorphonuclear leukocyte antibody-dependent cellular cytotoxicity in patients with LFA-1/OKM-1 deficiency.
J Immunol. 1984 Dec;133(6):2972-8
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Monoclonal antibody to a human brain-granulocyte-T lymphocyte antigen probably homologous to the W 3/13 antigen of the rat.
Eur J Immunol. 1980 Oct;10(10):745-9
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Integrins: a family of cell surface receptors.
Cell. 1987 Feb 27;48(4):549-54
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An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein.
Cell. 1984 Apr;36(4):897-906
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Epidermal keratinocytes express the adhesion molecule intercellular adhesion molecule-1 in inflammatory dermatoses.
J Invest Dermatol. 1989 May;92(5):746-50
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Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation.
J Immunol. 1983 Sep;131(3):1195-200
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Changes in vascular endothelium related to lymphocyte collections in diseased synovia.
Arthritis Rheum. 1983 Dec;26(12):1427-33
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T cell adhesion molecules.
FASEB J. 1988 Jul;2(10):2584-90
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Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1).
Cell. 1987 Dec 4;51(5):813-9
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The role of monocyte lymphocyte function-associated antigen 1 (LFA-1) in accessory cell function.
Eur J Immunol. 1987 Jul;17(7):943-7
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The lymphocyte function-associated antigen (LFA)-1 and CD2/LFA-3 pathways of antigen-independent human T cell adhesion.
J Immunol. 1987 Aug 15;139(4):1037-45
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Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface.
Nature. 1987 Oct 29-Nov 4;329(6142):846-8
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Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.
J Immunol. 1988 Nov 1;141(9):2980-5
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Human erythrocyte antigens: II. The In(Lu) gene regulates expression of an antigen on an 80-kilodalton protein of human erythrocytes.
Blood. 1984 Sep;64(3):599-606
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Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells.
J Biol Chem. 1988 Mar 25;263(9):4193-201
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Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion.
J Exp Med. 1987 Mar 1;165(3):677-92
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Very late activation antigens on rheumatoid synovial fluid T lymphocytes. Association with stages of T cell activation.
J Clin Invest. 1986 Sep;78(3):696-702
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The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes.
Nature. 1989 Jan 12;337(6203):179-81
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Identification of a human T lymphocyte surface protein associated with the E-rosette receptor.
J Exp Med. 1981 Jan 1;153(1):207-12
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Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha.
Cell. 1989 Jan 13;56(1):37-46
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Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors.
J Immunol. 1989 Mar 15;142(6):2046-51
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Rheumatoid arthritis: clinical features and pathogenetic mechanisms.
Med Clin North Am. 1986 Mar;70(2):263-84
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Redistribution of a major cell surface glycoprotein during cell movement.
J Cell Biol. 1984 Nov;99(5):1613-23
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A 19-kDa human erythrocyte molecule H19 is involved in rosettes, present on nucleated cells, and required for T cell activation. Comparison of the roles of H19 and LFA-3 molecules in T cell activation.
J Immunol. 1989 May 1;142(9):3013-20
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A unique epitope on the CD2 molecule defined by the monoclonal antibody 9-1: epitope-specific modulation of the E-rosette receptor and effects on T-cell functions.
Hum Immunol. 1986 Dec;17(4):388-405
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Adhesive protein receptors on hematopoietic cells.
Immunol Today. 1988 Apr;9(4):109-13
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Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.
J Immunol. 1987 Jun 15;138(12):4313-21
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Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens.
J Immunol. 1987 Jan 15;138(2):358-63
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Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man.
J Immunol. 1988 Sep 1;141(5):1615-23
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Human p85 glycoprotein bears three distinct epitopes defined by several monoclonal antibodies.
Mol Immunol. 1986 Jun;23(6):639-44
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Human medullary thymocyte p80 antigen and In(Lu)-related p80 antigen reside on the same protein.
Hum Immunol. 1986 Nov;17(3):311-24
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Structural heterogeneity of human Pgp-1 and its relationship with p85.
Immunogenetics. 1988;27(6):460-4
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Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.
Proc Natl Acad Sci U S A. 1987 May;84(10):3365-9
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The gene, MIC4, which controls expression of the antigen defined by monoclonal antibody F10.44.2, is on human chromosome 11.
Eur J Immunol. 1982 Aug;12(8):659-63
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Homing of hemopoietic precursor cells to the embryonic thymus: characterization of an invasive mechanism induced by chemotactic peptides.
J Cell Biol. 1986 Dec;103(6 Pt 2):2715-27
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Clonal analysis of human T cell activation by the Mycoplasma arthritidis mitogen (MAS).
Eur J Immunol. 1988 Nov;18(11):1733-7
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Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.
J Immunol. 1988 Mar 1;140(5):1401-7
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Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment.
Arthritis Rheum. 1989 Jan;32(1):22-30
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Mechanisms and regulation of lymphocyte migration.
Immunol Today. 1989 Jan;10(1):23-8
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The ligand of the erythrocyte receptor of T lymphocytes: expression on white blood cells and possible involvement in T cell activation.
J Immunol. 1986 Mar 15;136(6):2103-8
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Dendritic cell-lymphocyte clusters that form spontaneously in rheumatoid arthritis synovial effusions differ from clusters formed in human mixed leukocyte reactions.
J Clin Invest. 1988 Nov;82(5):1731-45
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The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions.
J Immunol. 1983 Aug;131(2):611-6
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Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).
J Immunol. 1986 Jul 1;137(1):245-54
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VLA-1: a T cell surface antigen which defines a novel late stage of human T cell activation.
Eur J Immunol. 1985 May;15(5):502-8
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T cell activation via CD2 [T, gp50]: the role of accessory cells in activating resting T cells via CD2.
J Immunol. 1986 Sep 1;137(5):1420-8
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Chromosome mapping of human cell surface molecules: monoclonal anti-human lymphocyte antibodies 4F2, A3D8, and A1G3 define antigens controlled by different regions of chromosome 11.
Somatic Cell Genet. 1983 May;9(3):333-44
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The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system.
Annu Rev Immunol. 1987;5:223-52
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CD44 antibody against In(Lu)-related p80, lymphocyte-homing receptor molecule inhibits the binding of human erythrocytes to T cells.
J Immunol. 1989 Dec 15;143(12):3944-8
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ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM.
Nature. 1988 Feb 18;331(6157):624-7
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Homing receptors and the control of lymphocyte migration.
Immunol Rev. 1986 Jun;91:39-60
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The structure of the human CD2 gene and its expression in transgenic mice.
EMBO J. 1988 Jun;7(6):1675-82
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Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95-kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or synovial endothelial cells.
J Cell Biol. 1987 Aug;105(2):983-90
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A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.
J Immunol. 1986 Aug 15;137(4):1270-4
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Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor beta-chain gene.
Nature. 1985 Jun 20-26;315(6021):666-9
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The CD2 ligand LFA-3 activates T cells but depends on the expression and function of the antigen receptor.
J Immunol. 1988 Sep 15;141(6):1904-11
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Homing receptors on human and rodent lymphocytes--evidence for a conserved carbohydrate-binding specificity.
Blood. 1987 Dec;70(6):1842-50
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Immune functions of human synovial cells. Phenotypic and T cell regulatory properties of macrophage-like cells that express HLA-DR.
Arthritis Rheum. 1982 May;25(5):488-501
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Synovial microenvironment-T cell interactions. Human T cells bind to fibroblast-like synovial cells in vitro.
Arthritis Rheum. 1988 Aug;31(8):947-55
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Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).
J Exp Med. 1988 Apr 1;167(4):1323-40
PMID: 3128630
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Primary structure of lymphocyte function-associated antigen 3 (LFA-3). The ligand of the T lymphocyte CD2 glycoprotein.
J Exp Med. 1987 Oct 1;166(4):923-32
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Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families.
Cell. 1988 Mar 25;52(6):925-33
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Phenotypic analysis of synovial tissue and peripheral blood lymphocytes isolated from patients with rheumatoid arthritis.
Arthritis Rheum. 1988 Oct;31(10):1230-8
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Monoclonal antibodies to CD2 and lymphocyte function-associated antigen 3 inhibit human thymic epithelial cell-dependent mature thymocyte activation.
J Immunol. 1987 Oct 15;139(8):2573-8
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Deficiency of lymphocyte function-associated antigen 3 (LFA-3) in paroxysmal nocturnal hemoglobinuria. Functional correlates and evidence for a phosphatidylinositol membrane anchor.
J Exp Med. 1987 Oct 1;166(4):1011-25
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LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes.
Hum Immunol. 1987 Jan;18(1):3-37
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Induction of intercellular adhesion molecule 1 on primary and continuous cell lines by pro-inflammatory cytokines. Regulation by pharmacologic agents and neutralizing antibodies.
J Immunol. 1988 Sep 1;141(5):1665-9
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Specific cell-adhesion mechanisms determining migration pathways of recirculating lymphocytes.
Annu Rev Immunol. 1987;5:201-22
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Cytokines and other mediators in rheumatoid arthritis.
Springer Semin Immunopathol. 1984;7(4):387-413
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Monoclonal antibodies OKT 11 and OKT 11A have pan-T reactivity and block sheep erythrocyte "receptors".
Eur J Immunol. 1982 Jan;12(1):81-6
PMID: 6977453
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Site-selective homing of antigen-primed lymphocyte populations can play a crucial role in the efferent limb of cell-mediated immune responses in vivo.
J Immunol. 1985 May;134(5):2900-7
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Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene.
J Clin Invest. 1983 Jun;71(6):1878-86
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Pathways to chronic inflammation in rheumatoid synovitis.
Fed Proc. 1987 Jan;46(1):113-7
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Further characterization of erythrocyte p80 and the membrane protein defect of In(Lu) Lu(a-b-) erythrocytes.
Blood. 1987 Nov;70(5):1475-81
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A human T lymphocyte differentiation marker defined by monoclonal antibodies that block E-rosette formation.
J Immunol. 1981 Jun;126(6):2117-22
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