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PMID: 2981809 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Regulation of expression of the crp gene of Escherichia coli K-12: in vivo study.

Journal of bacteriology ·Vol. 161 ·No. 1 ·1985-01-00 ·Pages 454-7

Cossart P, Gicquel-Sanzey B

Abstract

Expression of the crp gene was studied in vivo by use of a crp-lacZ gene fusion first constructed on a plasmid and then transferred onto the chromosome. Our in vivo data confirm the in vitro findings that crp is negatively autoregulated via the cyclic AMP-catabolite gene activator protein complex. We present evidence that gene crp is repressed by glucose.

MeSH Terms
Cyclic AMP/pharmacology DNA, Recombinant Escherichia coli/genetics Gene Expression Regulation/drug effects Genes, Bacterial Glucose/pharmacology Lac Operon Plasmids Receptors, Cyclic AMP/genetics Transcription, Genetic Transduction, Genetic
Chemicals
DNA, Recombinant Receptors, Cyclic AMP Cyclic AMP Glucose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Cossart P
Gicquel-Sanzey B
References (16)
16 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.161.1.454-457.1985
Published
1985-01-00
Pages
454-7
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC214896
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.161.1.454-457.1985 PMC Full Text View journal details
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