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PMID: 2998763 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Retroviral characteristics of the long terminal repeat of murine E.Tn sequences.

The EMBO journal ·Vol. 4 ·No. 11 ·1985-11-00 ·Pages 2911-5

Kaghad M, Maillet L, Brûlet P

Abstract

E.Tn sequences form a family of long moderately repeated sequences which are abundantly transcribed in the pluripotent cell lineage between day 3.5 and 7.5 of early mouse embryogenesis. The structure of the long terminal repeat (LTR) bordering the E.Tn sequences has been investigated by nucleotide sequencing, primer extension and S1 mapping experiments. This has allowed the identification of U3, R and U5 domains, and of several other structural features all of which are characteristics of retroviral LTRs.

MeSH Terms
Animals Base Sequence Cell Line Cloning, Molecular DNA Restriction Enzymes DNA Transposable Elements DNA, Single-Stranded/genetics Endonucleases Mice Nucleic Acid Conformation Repetitive Sequences, Nucleic Acid Retroviridae/genetics Single-Strand Specific DNA and RNA Endonucleases
Chemicals
DNA Transposable Elements DNA, Single-Stranded Endonucleases DNA Restriction Enzymes Single-Strand Specific DNA and RNA Endonucleases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Kaghad M
Maillet L
Brûlet P
References (17)
17 references, click to expand
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Article Info
Journal
The EMBO journal
Abbr.
EMBO J
ISSN
0261-4189
Published
1985-11-00
Pages
2911-5
Language
English
Region
England
NLM ID
8208664
PMCID
PMC554597
Subset
IM
Databases
GENBANK
M13187, M13188, X03063, X03064
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