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PMID: 3033295 Published · ppublish English Journal Article

Human papillomavirus type 18 DNA is integrated at a single chromosome site in cervical carcinoma cell line SW756.

Journal of virology ·Vol. 61 ·No. 5 ·1987-05-00 ·Pages 1682-5

Popescu NC, Amsbaugh SC, DiPaolo JA

Abstract

SW756, a cervical carcinoma cell line, has multiple copies of human papillomavirus type 18 DNA sequences. The integration site of human papillomavirus type 18 DNA was localized by in situ hybridization to chromosome 12 at band q13. This single integration site corresponds to a heritable fragile site, which may have facilitated the integration of the viral DNA.

MeSH Terms
Carcinoma/genetics,microbiology Cell Line Cell Transformation, Viral Chromosome Banding Chromosome Mapping Chromosomes, Human, Pair 12 Female Humans Nucleic Acid Hybridization Papillomaviridae/genetics Uterine Cervical Neoplasms/genetics,microbiology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Popescu N C
Amsbaugh S C
DiPaolo J A
References (21)
21 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.61.5.1682-1685.1987
Published
1987-05-00
Pages
1682-5
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC254155
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.61.5.1682-1685.1987 PMC Full Text View journal details
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