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PMID: 3039160 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Genome segment reassortment between two serotypes of bluetongue virus in a natural host.

Journal of virology ·Vol. 61 ·No. 9 ·1987-09-00 ·Pages 2670-4

Stott JL, Oberst RD, Channell MB, Osburn BI

Abstract

The occurrence of genome segment reassortment between two antigenically related orbiviruses was demonstrated in cattle. Individual virus clones were isolated by cell culture plaque assays directly from the blood of a calf infected with two serotypes of bluetongue virus. The majority (89%) of progeny viruses isolated from the calf represented reassortant viruses. A minimum of six genome segments participated in reassortment, with 16 unique reassortant constellations being identified. Such genome segment reassortment between unique, though antigenically related, orbiviruses has undoubtedly played a major role in generating the extensive phenotypic and genotypic diversity that is characteristic of this serogroup.

MeSH Terms
Animals Antibodies, Viral/analysis Bluetongue virus/genetics,immunology Cattle Genes, Viral Genotype Male RNA, Viral/analysis Reoviridae/genetics Serotyping
Chemicals
Antibodies, Viral RNA, Viral
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Stott J L
Oberst R D
Channell M B
Osburn B I
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25 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.61.9.2670-2674.1987
Published
1987-09-00
Pages
2670-4
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC255769
Subset
IM
Grants
NCRR NIH HHS · 2S07RR05457 · United States
External Links
PubMed source DOI: 10.1128/JVI.61.9.2670-2674.1987 PMC Full Text View journal details
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