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PMID: 3089144 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Previously undescribed 6.6-kilobase R plasmid in penicillinase-producing Neisseria gonorrhoeae.

Antimicrobial agents and chemotherapy ·Vol. 29 ·No. 6 ·1986-06-00 ·Pages 1095-7

Gouby A, Bourg G, Ramuz M

Abstract

A penicillin-resistant Neisseria gonorrhoeae strain was isolated. The resistance was due to the production of TEM-1 beta-lactamase encoded by a plasmid. This 6.6-kilobase plasmid was compared with the previously known 7.4- and 5.3-kilobase penicillin R plasmids of N. gonorrhoeae.

MeSH Terms
DNA, Bacterial/biosynthesis Neisseria gonorrhoeae/enzymology,genetics Nucleic Acid Hybridization Penicillinase/metabolism R Factors
Chemicals
DNA, Bacterial Penicillinase
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gouby A
Bourg G
Ramuz M
References (18)
18 references, click to expand
  1. Evolutionary analysis of the 7.1-kb beta-lactamase-specifying R-plasmid of Neisseria gonorrhoeae by restriction endonucleases.
    J Bacteriol. 1983 Jun;154(3):1498-501 PMID: 6304017
  2. Penicillinase-producing Neisseria gonorrhoeae: a molecular comparison of 5.3-kb and 7.4-kb beta-lactamase plasmids.
    J Bacteriol. 1982 Sep;151(3):1171-5 PMID: 6286592
  3. Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria.
    Microbiol Rev. 1983 Sep;47(3):361-409 PMID: 6355806
  4. [Epidemiological surveillance of beta-lactamase-producing gonococci. II--Characterization of plasmids of 66 strains isolated in France (May 1979-March 1983)].
    Pathol Biol (Paris). 1984 Dec;32(10):1013-8 PMID: 6440097
  5. A new beta-lactamase plasmid in Neisseria gonorrhoeae.
    J Antimicrob Chemother. 1985 Feb;15(2):247-50 PMID: 2984155
  6. Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate.
    Antimicrob Agents Chemother. 1972 Apr;1(4):283-8 PMID: 4208895
  7. A direct spectrophotometric assay and determination of Michaelis constants for the beta-lactamase reaction.
    Anal Biochem. 1975 Jan;63(1):17-26 PMID: 803320
  8. The use of analytical isoelectric focusing for detection and identification of beta-lactamases.
    J Gen Microbiol. 1975 May;88(1):169-78 PMID: 807678
  9. Detection of specific sequences among DNA fragments separated by gel electrophoresis.
    J Mol Biol. 1975 Nov 5;98(3):503-17 PMID: 1195397
  10. Beta-lactamase-producing, penicillin-resistant gonococcus.
    Lancet. 1976 Sep 25;2(7987):656-7 PMID: 60518
  11. Plasmid-mediated beta-lactamase production in Neisseria gonorrhoeae.
    Antimicrob Agents Chemother. 1977 Mar;11(3):528-33 PMID: 404964
  12. Molecular characterization of two beta-lactamase-specifying plasmids isolated from Neisseria gonorrhoeae.
    J Bacteriol. 1977 Aug;131(2):557-63 PMID: 407214
  13. Evidence for two distinct types of penicillinase-producing Neisseria gonorrhoeae.
    Lancet. 1977 Nov 12;2(8046):993-5 PMID: 72949
  14. Purification by affinity chromatography and properties of a beta-lactamase isolated from Neisseria gonorrhoeae.
    Antimicrob Agents Chemother. 1979 Feb;15(2):229-34 PMID: 106775
  15. Penicillinase-producing Neisseria gonorrhoeae in the Netherlands: epidemiology and genetic and molecular characterization of their plasmids.
    Antimicrob Agents Chemother. 1980 Nov;18(5):789-97 PMID: 6778387
  16. Deoxyribonucleic acid modifications and restriction endonuclease production in Neisseria gonorrhoeae.
    J Bacteriol. 1981 Feb;145(2):788-95 PMID: 6257650
  17. [Isolation and characterization of a beta-lactamase-specifying plasmid in a strain of "neisseria gonorrhoeae" (author's transl)].
    Ann Microbiol (Paris). 1981 May-Jun;132(3):283-92 PMID: 6271037
  18. Characterization of ampicillin resistance plasmids of Haemophilus ducreyi and Neisseria gonorrhoeae with regard to location of origin of transfer and mobilization by a conjugative plasmid of Haemophilus ducreyi.
    J Bacteriol. 1983 Oct;156(1):437-40 PMID: 6311803
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.29.6.1095
Published
1986-06-00
Pages
1095-7
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC180507
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.29.6.1095 PMC Full Text View journal details
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