Chicken embryo model for type III group B beta-hemolytic streptococcal septicemia.
A lethal septicemia was induced in 11- and 12-day-old chicken embryos with intravenous inoculation of relatively small numbers of a clinical isolate (GBBHS-III-Bell) or a reference strain (GBBHS-III-D136-C) of group B beta-hemolytic streptococci (GBBHS). GBBHS-III-Bell was more virulent than GBBHS-III-D136-C, and 11-day-old chicken embryos were more susceptible than 12-day-old chicken embryos. Type-specific rabbit antisera protected the embryos from bacterial challenge, and this protective effect was absorbed with homologous but not heterologous GBBHS strains. A heterologous antiserum and normal rabbit sera provided some protection, which could be absorbed with either homologous or heterologous GBBHS strains. The chicken embryo is a suitable animal model for the study of infection and immunity with GBBHS type III.
18 references, click to expand
-
Assessment of group B streptococcal opsonins in human and rabbit serum by neutrophil chemiluminescence.J Clin Invest. 1976 Dec;58(6):1379-87 PMID: 62761
-
Antigenic specificity of opsonophagocytic antibodies in rabbit anti-sera to group B streptococci.J Immunol. 1977 Feb;118(2):673-8 PMID: 65433
-
Summary of the workshop on perinatal infections due to group B Streptococcus.J Infect Dis. 1977 Jul;136(1):137-52 PMID: 69669
-
Correlation of maternal antibody deficiency with susceptibility to neonatal group B streptococcal infection.N Engl J Med. 1976 Apr 1;294(14):753-6 PMID: 768760
-
Immunity to the group B streptococci: interaction of serum and macrophages with types Ia, Ib, and Ic.J Exp Med. 1976 May 1;143(5):1186-98 PMID: 772153
-
The chick embryo in studies of virulence and immunity with Neisseria Gonorrhoeae.Rev Can Biol. 1975 Dec;34(4):213-20 PMID: 819971
-
Protection against group B meningococcal disease. I. Comparison of group-specific and type-specific protection in the chick embryo model.J Exp Med. 1976 Aug 1;144(2):319-29 PMID: 822114
-
Multiple mouse-protective antibodies directed against group B streptococci. Special reference to antibodies effective against protein antigens.J Exp Med. 1975 Jul 1;142(1):165-79 PMID: 1097573
-
Transfer of immunoglobulins and antibodies in the hen's egg.Immunology. 1970 Jul;19(1):157-67 PMID: 4098593
-
Pathogenesis and immunology of experimental gonococcal infection: virulence of colony types of Neisseria gonorrhoeae for chicken embryos.Infect Immun. 1973 Dec;8(6):919-24 PMID: 4206345
-
Opsonin system of the group B streptococcus.Infect Immun. 1974 Dec;10(6):1315-20 PMID: 4215762
-
Non-specific antimicrobial defences of the avian egg, embryo and neonate.Biol Rev Camb Philos Soc. 1974 Feb;49(1):15-49 PMID: 4594672
-
Group B streptococcal infections in infants. The importance of the various serotypes.JAMA. 1974 Nov 25;230(8):1158-60 PMID: 4608888
-
The chick embryo for the study of infection and immunity.J Infect Dis. 1970 Jun;121(6):660-3 PMID: 4912074
-
The chick embryo neutralization test in the assay of meningococcal antibody. 3. Dynamics and specificity of the sero-protection test.Rev Can Biol. 1971 Mar;30(1):1-9 PMID: 4998556
-
Phagocytosis as related to the reticuloendothelial system (RES) in the developing chick.Growth. 1969 Mar;33(1):47-56 PMID: 5790346
-
Antibody production in avian embryos and young chicks.J Gen Microbiol. 1954 Jun;10(3):398-410 PMID: 13174763
-
A TECHNIQUE FOR THE INTRAVENOUS INOCULATION OF CHICK EMBRYOS.Science. 1940 Sep 13;92(2385):245-6 PMID: 17814314
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