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PMID: 3967288 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Immunocytochemical demonstration of retinal S-antigen in the pineal organ of four mammalian species.

Cell and tissue research ·Vol. 239 ·No. 1 ·1985-00-00 ·Pages 81-5

Korf HW, Møller M, Gery I, Zigler JS, Klein DC

Abstract

By means of immunocytochemistry retinal S-antigen is selectively demonstrated in retinal photoreceptor cells of the rat and in pinealocytes of the hedgehog, rat, gerbil and cat. Brain areas surrounding the pineal organ are immunonegative. The immunoreactive material is evenly distributed in the perikarya of the cells. Occasionally, inner segments of retinal photoreceptors and processes of pinealocytes are also stained. The outer segments of retinal photoreceptors display a strong immunoreaction. In both pinealocytes and retinal photoreceptors the intensity of the immunoreaction varied considerably among individual cells. The immunocytochemical demonstration of retinal S-antigen in mammalian pinealocytes indicates that these cells still bear characteristics of photoreceptors. This finding is in accord with the concept that mammalian pinealocytes are derived from pineal photoreceptor cells of poikilothermic vertebrates.

MeSH Terms
Animals Antigens/isolation & purification Arrestin Cats Female Gerbillinae Hedgehogs Immunochemistry Male Photoreceptor Cells/immunology Pineal Gland/immunology Rats Retina/immunology Species Specificity
Chemicals
Antigens Arrestin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Korf H W
Møller M
Gery I
Zigler J S
Klein D C
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20 references, click to expand
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Article Info
Journal
Cell and tissue research
Abbr.
Cell Tissue Res
ISSN
0302-766X
DOI
10.1007/BF00214906
Published
1985-00-00
Pages
81-5
Language
English
Region
Germany
NLM ID
0417625
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00214906 View journal details
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