Identification of competence-repressing factors during log-phase growth of Haemophilus influenzae.

Journal of bacteriology ·Vol. 109 ·No. 2 ·1972-02-00 ·Pages 560-4

Miller DH, Huang PC

Abstract

Metabolic factors that suppress development of competence in Haemophilus influenzae during growth in the synthetic medium MI(c) have been identified. These include inosine, nicotinamide adenine dinucleotide, glycerol, and uracil. It is also possible to initiate competence in the presence of these substances if the oxygen tension in the culture is temporarily reduced.

MeSH Terms

Cell Division/drug effects Culture Media DNA, Bacterial/pharmacology Densitometry Fumarates/pharmacology Glycerol/pharmacology Haemophilus influenzae/drug effects,growth & development,metabolism Inosine/pharmacology Lactates/pharmacology NAD/pharmacology Oxygen Partial Pressure Spectrophotometry Uracil/pharmacology

Chemicals

Culture Media DNA, Bacterial Fumarates Lactates NAD Uracil Inosine Glycerol Oxygen

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Miller D H

Huang P C

References (12)

12 references, click to expand

REQUIREMENTS FOR TRANSFORMATION IN BACILLUS SUBTILIS.
J Bacteriol. 1961 May;81(5):741-6 PMID: 16561900
Defined nongrowth media for stage II development of competence in Haemophilus influenzae.
J Bacteriol. 1970 Feb;101(2):517-24 PMID: 5308771
STUDIES ON THE PHENOTYPIC EXPRESSION OF COMPETENCE IN NEISSERIA MENINGITIDIS.
Acta Pathol Microbiol Scand. 1965;64:119-29 PMID: 14320671
The regulation of synthesis of Krebs cycle enzymes in Neurospora by catabolite and end product repression.
Eur J Biochem. 1970 Apr;13(3):548-53 PMID: 5444160
Time-dependent effects of inosine on competence development in Haemophilus influenzae.
J Bacteriol. 1970 Nov;104(2):775-9 PMID: 5312691
Catabolite repression of beta-galactosidase synthesis in Escherichia coli.
Biochem J. 1966 Aug;100(2):336-53 PMID: 5338805
THE INFLUENCE OF NITRATE AND NITRITE REDUCTION ON CATABOLITE REPRESSION IN ESCHERICHIA COLI.
Biochim Biophys Acta. 1965 May 4;100:553-66 PMID: 14347951
Development of competence of Haemophilus influenzae.
J Bacteriol. 1965 Oct;90(4):911-20 PMID: 5294817
Competence mutants: isolation of transformation deficient strains of Haemophilus influenzae.
Nature. 1970 Aug 1;227(5257):515-7 PMID: 5310646
TRANSFORMATION TO PROTOTROPHY AND POLYGLUTAMIC ACID SYNTHESIS IN BACILLUS LICHENIFORMIS.
J Bacteriol. 1964 Jul;88:220-5 PMID: 14197892
Defined medium for growth of Haemophilus influenzae.
J Bacteriol. 1970 Feb;101(2):513-6 PMID: 5308770
PENETRATION OF DEOXYRIBONUCLEIC ACID INTO HEMOPHILUS INFLUENZAE.
Biochim Biophys Acta. 1963 Sep 17;76:25-39 PMID: 14068558

Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.109.2.560-564.1972

Published

1972-02-00

Pages

560-4

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC285177

Subset

External Links

PubMed source DOI: 10.1128/jb.109.2.560-564.1972 PMC Full Text View journal details

Analysis Services

Identification of competence-repressing factors during log-phase growth of Haemophilus influenzae.

Contact

WeChat Official Account