Murine intracisternal A type particles fail to separate from the membrane of the endoplasmic reticulum.

Journal of virology ·Vol. 14 ·No. 5 ·1974-11-00 ·Pages 1304-6

Perk K, Dahlberg JE

Abstract

Analysis of serial sections of murine cells containing intracisternal A particles revealed that over 99% of all A particles remain in a budding configuration. This indicates that these particles fail to detach from the membrane of the endoplasmic reticulum. This observation explains how, despite their intracellular abundance in certain murine tumors, no extracellular A-type particles can be found.

MeSH Terms

Animals Culture Techniques Endoplasmic Reticulum/microbiology Inclusion Bodies, Viral/ultrastructure Mice Microscopy, Electron Plasmacytoma/microbiology,pathology Rhabdomyosarcoma/microbiology,pathology

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Perk K

Dahlberg J E

References (15)

15 references, click to expand

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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.14.5.1304-1306.1974

Published

1974-11-00

Pages

1304-6

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC355649

Subset

External Links

PubMed source DOI: 10.1128/JVI.14.5.1304-1306.1974 PMC Full Text View journal details

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Murine intracisternal A type particles fail to separate from the membrane of the endoplasmic reticulum.

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