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PMID: 4595301 Published · ppublish English Journal Article

Genetic recombination in bacteriophage phi chi 174.

Journal of virology ·Vol. 13 ·No. 4 ·1974-04-00 ·Pages 898-907

Benbow RM, Zuccarelli AJ, Davis GC, Sinsheimer RL

Abstract

Genetic recombination in bacteriophage phiX174 usually takes place early in the infection process and involves two parental replicative form (double-stranded) DNA molecules. The host recA protein is required; none of the nine known phiX174 cistron products is essential. The products of a single recombination event are nonreciprocal and asymmetric. Typically, only one of the parental genotypes and one recombinant genotype are recovered from a single cell. An alternative, less efficient recombination mechanism which requires an active phiX174 cistron A protein is observed in the absence of the host recA gene product.

MeSH Terms
Alleles Chromosome Mapping Coliphages DNA Viruses Escherichia coli Genotype Mutation Recombination, Genetic
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Benbow R M
Zuccarelli A J
Davis G C
Sinsheimer R L
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27 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.13.4.898-907.1974
Published
1974-04-00
Pages
898-907
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC355388
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.13.4.898-907.1974 PMC Full Text View journal details
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