Home LiteratureArticle Details
PMID: 4613945 Published · ppublish ger English Abstract Journal Article Review

[Molecular biology of the lymphocyte of the chronic lymphocytic leukemia (author's transl)].

Makromolekulare Besonderheiten des Lymphocyten der chronisch-lymphatischen Leukämie (CLL)

Klinische Wochenschrift ·Vol. 52 ·No. 23 ·1974-12-01 ·Pages 1093-102

Seeber S, Schmidt CG

Abstract

暂无摘要

MeSH Terms
Antibody Formation B-Lymphocytes/immunology Blood Proteins Chromatin/metabolism DNA, Neoplasm/biosynthesis Humans Hybridization, Genetic Lectins Leukemia, Lymphoid/immunology,metabolism,pathology Lymphocytes/metabolism Macromolecular Substances Protein Binding RNA, Neoplasm/biosynthesis Ribosomes/metabolism
Chemicals
Blood Proteins Chromatin DNA, Neoplasm Lectins Macromolecular Substances RNA, Neoplasm
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Seeber S
Schmidt C G
References (107)
107 references, click to expand
  1. Defective control of ribosomal RNA processing in stimulated leukemic lymphocytes.
    J Clin Invest. 1971 Dec;50(12):2485-97 PMID: 5129303
  2. Mitochondrial DNA: Advances, Problems, and Goals.
    Science. 1969 Jul 4;165(3888):25-35 PMID: 17840675
  3. Immunoglobulins on the surface of lymphocytes. IV. Distribution in hypogammaglobulinemia, cellular immune deficiency, and chronic lymphatic leukemia.
    J Clin Invest. 1971 Nov;50(11):2368-75 PMID: 4999540
  4. Ribonucleic acid-deoxyribonucleic acid hybridization and hybridization--competition studies of the rapidly labeled ribonucleic acid from normal and chronic lymphocytic leukemia lymphocytes.
    Biochemistry. 1969 Jan;8(1):275-82 PMID: 4975911
  5. Lymphocyte actinomycin binding capacity in chronic lymphocytic leukaemia.
    Experientia. 1972 Dec 15;28(12):1484 PMID: 4120194
  6. Complex mitochondrial DNA in human tumors.
    Cancer Res. 1973 May;33(5):1065-70 PMID: 4512952
  7. Similarity of ribosomal and ribosomal precursor RNA's from rat liver and the Novikoff ascites hepatoma.
    Cancer Res. 1973 Dec;33(12):3312-8 PMID: 4357360
  8. Radiation stimulated incorporation of thymidine into the DNA of human lymphocytes.
    Nature. 1968 Feb 3;217(5127):455-6 PMID: 4868056
  9. Proteins in nucleocytoplasmic interactions. I. The fundamental characteristics of the rapidly migrating proteins and the slow turnover proteins of the Amoeba proteus nucleus.
    J Cell Biol. 1967 Jun;33(3):637-44 PMID: 6036526
  10. Changes of nuclear RNA in hepatomas as revealed by RNA-DNA hybridization.
    Biochim Biophys Acta. 1969 Mar 18;179(1):129-35 PMID: 4306884
  11. Differences in nuclear RNA labelling patterns of Burkitt lymphoma, leukaemic lymphosarcoma and various human leukaemias.
    Klin Wochenschr. 1973 Jul 1;51(3):680-4 PMID: 4518361
  12. The nucleolar RNA of minimal deviation hepatomas.
    Cancer Res. 1968 Jun;28(6):1126-37 PMID: 4298058
  13. The total N-acetyl neuraminic acid content of human normal and lymphatic leukaemic lymphocytes.
    Br J Cancer. 1973 Feb;27(2):114-9 PMID: 4511987
  14. Compact filamentous bodies of nuclei and nucleoli of human prostate gland.
    Exp Cell Res. 1971 Jan;64(1):133-9 PMID: 5541960
  15. Surface immunoglobulin-moieties on lymphoid cells.
    Exp Cell Res. 1970 Sep;62(1):133-48 PMID: 4991453
  16. New species of hybridizable nuclear RNA in breast cancer cells.
    Cancer Res. 1970 Jun;30(6):1833-40 PMID: 5457944
  17. Pokeweed mitogen response of lymphocytes in chronic lymphocytes in chronic lymphocytic leukemia: a fine structural study.
    Blood. 1973 Oct;42(4):591-600 PMID: 4795012
  18. Lymphocyte lysosomes and lysosomal enzymes in chronic lymphocytic leukemia.
    Blood. 1973 Apr;41(4):511-8 PMID: 4688866
  19. Virus-like particles in the lymphocytes of a patient with chronic lymphocytic leukemia.
    Blood. 1963 Apr;21:509-12 PMID: 14004035
  20. Adenylate cyclase activity in normal and leukemic human leukocytes as determined by a radioimmunoassay for cyclic AMP.
    Biochim Biophys Acta. 1973 Feb 28;297(2):378-83 PMID: 4350264
  21. Incorporation of uridine- 3 H and sodium acetate- 14 C in lymphocytes derived from normal and leukemic individuals.
    Cancer Res. 1972 Sep;32(9):1833-6 PMID: 4509040
  22. Surface immunoglobulins on lymphocytes in chronic lymphocytic leukaemia and lymphosarcoma.
    Br J Haematol. 1973 May;24(5):563-9 PMID: 4541301
  23. Human leukemic polyribosomes.
    Proc Soc Exp Biol Med. 1967 Apr;124(4):1125-31 PMID: 5229005
  24. Leukocyte labeling with 51 chromium. IV. The kinetics of chronic lymphocytic leukemic lymphocytes.
    Blood. 1973 Jan;41(1):155-62 PMID: 4682076
  25. Uridine incorporation and RNA synthesis during stimulation of lymphocytes by PHA.
    Exp Cell Res. 1970 Dec;63(2):411-21 PMID: 4099169
  26. Isolation of rapidly labelled nuclear RNA of high specific activity from human leukaemic cells.
    Klin Wochenschr. 1973 Jul 1;51(3):677-9 PMID: 4749521
  27. New species of rapidly hybridizing RNA in contact-inhibited as well as transformed hamster cell lines.
    Cancer Res. 1972 Mar;32(3):506-10 PMID: 4334411
  28. [DNA and RNA synthesis in benign and malignant lymphomas].
    Klin Wochenschr. 1967 Jun 15;45(12):609-18 PMID: 4898318
  29. [Defective synthesis of ribosomal nucleic acids in human leukemic cells (author's transl)].
    Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1974;82(2):159-73 PMID: 4278588
  30. Isolation of normal T cells in chronic lymphatic leukaemia.
    Lancet. 1973 Jan 20;1(7795):126-9 PMID: 4118467
  31. Immunoglobulins on the surface of human lymphocytes.
    Lancet. 1971 Oct 16;2(7729):850-2 PMID: 4106875
  32. Occurrence of complex mitochondrial DNA in normal tissues.
    Nature. 1968 Dec 7;220(5171):976-9 PMID: 5701854
  33. Actinomycin binding capacity in human leukaemic lymphoid cells.
    Acta Haematol. 1972;48(2):89-97 PMID: 4117055
  34. Two-dimensional polyacrylamide gel electrophoresis of acid extractable nuclear proteins of normal rat liver and Novikoff hepatoma ascites cells.
    Biochem Biophys Res Commun. 1973 Apr 16;51(4):956-66 PMID: 4349999
  35. Thoracic-duct and blood lymphocytes in cancer.
    Lancet. 1973 Aug 4;2(7823):264-5 PMID: 4124456
  36. Different gene expression for ribosomal RNA of AH-130 tumor and embryonic and adult rat liver.
    Biochim Biophys Acta. 1971 Mar 11;232(2):352-8 PMID: 5553682
  37. A further contribution to the question of the incidence of nucleoli in the nuclei of mature lymphocytes in man.
    Folia Biol (Praha). 1961;7:268-74 PMID: 13914025
  38. Two-dimensional polyacrylamide gel electrophoresis of saline-soluble nuclear proteins of leukemic and normal human lymphocyte nuclear proteins.
    Physiol Chem Phys. 1973;5(6):503-10 PMID: 4786102
  39. Characteristics of RNA synthesized in vitro by lymphocytes of chronic lymphocytic leukemia.
    J Lab Clin Med. 1967 Jan;69(1):47-61 PMID: 6018070
  40. Possible defect in RNA metabolism in leukemic cells.
    Cancer. 1968 Mar;21(3):357-67 PMID: 5237297
  41. Preparation and partial fractionation of nonhistone chromosomal proteins from human diploid fibroblasts.
    Arch Biochem Biophys. 1973 Sep;158(1):89-96 PMID: 4199638
  42. Kinetics of lymphocytes in chronic lymphocytic leukemia: studies using continuous 3H-thymidine infusion in two patients.
    Blood. 1973 Oct;42(4):623-36 PMID: 4778708
  43. EFFECTS OF THIOACETAMIDE ON THE COMPOSITION AND BIOSYNTHESIS OF NUCLEOLAR AND NUCLEAR RIBONUCLEIC ACID IN RAT LIVER.
    J Biol Chem. 1965 Apr;240:1742-9 PMID: 14285518
  44. Structural analysis of nucleolar precursors of ribosomal ribonucleic acids. II. Polypurine sequences as chemical markers of processing of nucleolar 45 S ribonucleic acid.
    J Biol Chem. 1971 Dec 10;246(23):7151-8 PMID: 4331433
  45. Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.
    Science. 1968 Aug 9;161(3841):529-40 PMID: 4874239
  46. A further contribution to the demonstration of RNA and nucleoli of blood cells in smear preparations.
    Folia Haematol Int Mag Klin Morphol Blutforsch. 1969;91(4):381-94 PMID: 4184463
  47. Control of rRNA production in non-growing cells.
    Nat New Biol. 1972 Mar 8;236(62):32 PMID: 4503813
  48. Further evidence of heterogeneity of ribosomal RNA in various rat tissues.
    Biochim Biophys Acta. 1972 Mar 24;262(3):320-7 PMID: 5038685
  49. Developmental pathway of granular and beaded nuclear bodies from nucleoli.
    J Ultrastruct Res. 1972 Jul;40(1):55-67 PMID: 4338390
  50. [On the morphology of blood lymphocytes after the administration of pyrogens and ACTH].
    Wien Z Inn Med. 1963 Feb;44:110-5 PMID: 13978644
  51. Reaction of normal human lymphocytes and chronic lymphocytic leukemia cells with an antithymocyte antiserum.
    Blood. 1973 Mar;41(3):417-23 PMID: 4570349
  52. Impaired of ribosomal precursor RNA in blast cells of acute leukemia.
    Acta Haematol. 1971;45(3):201-8 PMID: 4997714
  53. Dameshek W. Chronic lymphocytic leukemia-an accumulative disease of immunologically incompetent lymphocytes. Blood. 1967;29(4):566-584.
    Blood. 2016 Jul 28;128(4):465 PMID: 27471229
  54. Ultrastructure of blood lymphocytes from chronic lymphocytic and lymphosarcoma cell leukemia.
    J Natl Cancer Inst. 1972 Jan;48(1):51-64 PMID: 4652376
  55. Identification of human T and B lymphocytes in normal peripheral blood and in chronic lymphocytic leukaemia.
    Lancet. 1971 Oct 9;2(7728):788-91 PMID: 4106607
  56. The lymphocyte of chronic lymphatic leukemia. I. Electron microscopy--onset.
    Cancer. 1970 Oct;26(4):895-903 PMID: 5506611
  57. Protein synthesis by ribosomes from blood lymphocytes of normals and patients with chronic lymphocytic leukemia (CLL).
    Proc Soc Exp Biol Med. 1972 Dec;141(3):839-41 PMID: 4645769
  58. An unusual cytoplasmic ribosomal structure in pathologic lymphocytes.
    Blood. 1973 Mar;41(3):439-49 PMID: 4690141
  59. Transcription from chromatins of human lymphocytic leukemia cells and normal lymphocytes.
    Cancer Res. 1973 Feb;33(2):428-34 PMID: 4510929
  60. On the possibility of nuclear protein involvement in the control of DNA synthesis in Amoeba proteus.
    Exp Cell Res. 1969 Apr;55(1):144-6 PMID: 5780788
  61. Electron Microscopic investigations on sections from lymph nodes and bone marrow in malignant blood diseases.
    Blood. 1957 Mar;12(3):278-94 PMID: 13403990
  62. [Base analyses, oligonucleotide sequences and marking kinetics of high molecular ribonucleic acids of human leukemias and lymphomas].
    Verh Dtsch Ges Inn Med. 1973;79:511-3 PMID: 4790279
  63. Partial failure of methylation and cleavage of 45S RNA in the blast cells of acute leukaemia.
    Nature. 1970 Jun 20;226(5251):1163-5 PMID: 5267418
  64. ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS.
    Proc Natl Acad Sci U S A. 1964 May;51:786-94 PMID: 14172992
  65. Comparison of nucleolar proteins of normal rat liver and Novikoff hepatoma ascites cells by two-dimensional polyacrylamide gel electrophoresis.
    Proc Natl Acad Sci U S A. 1973 May;70(5):1316-20 PMID: 4351171
  66. Studies on the primary structure of ribosomal 28 S ribonucleic acid and its nucleolar precursors. Isolation of an electrophoretically homogeneous fragment rich in guanylic and cytidylic acids.
    J Biol Chem. 1969 Oct 25;244(20):5471-80 PMID: 4310597
  67. Ribonucleic acid metabolism in lymphocytes stimulated by phytohemagglutinin. II. Rapidly synthesized ribonucleic acid and te production of ribosomal ribonucleic acid.
    J Biol Chem. 1968 Jan 10;243(1):34-43 PMID: 5635946
  68. Deoxyribonucleic acid (DNA) repair replication of ultraviolet (UV) irradiated normal and leukemic leukocytes.
    J Lab Clin Med. 1969 Jul;74(1):109-18 PMID: 5256171
  69. Mutagenic DNA polymerase in human leukemic cells.
    Proc Natl Acad Sci U S A. 1973 Jan;70(1):245-9 PMID: 4346035
  70. Thymus-derived proliferating lymphocytes in chronic lymphocytic leukaemia.
    Lancet. 1973 Aug 4;2(7823):263-4 PMID: 4124455
  71. Two-dimensional polyacrylamide gel electrophoresis of chromatin proteins of normal rat liver and Novikoff hepatoma ascites cells.
    Biochem Biophys Res Commun. 1973 Aug 21;53(4):1067-76 PMID: 4356049
  72. Comparative oligonucleotide sequences of 28 S ribosomal RNA normal liver and Novikoff hepatoma ascites cells.
    Cancer Res. 1971 Dec;31(12):1888-94 PMID: 4330434
  73. On the synthesis of RNA in lymphocytes stimulated by phytohemagglutinin. 1. Induction of uridine-kinase and the conversion of uridine to UTP.
    Eur J Biochem. 1968 Apr;4(3):401-6 PMID: 5690132
  74. [The morphology of nucleoli in lymphocytes of the peripheral blood].
    Acta Haematol. 1972;48(2):104-15 PMID: 4117054
  75. Thymidylat-synthetase in white blood cells and bone marrow under normal and pathological conditions.
    Klin Wochenschr. 1971 Jul 1;49(13):755-62 PMID: 5284246
  76. Studies in chronic lymphocytic leukemia: further studies of the proliferative abnormality of the blood lymphocyte.
    Blood. 1969 Feb;33(2):313-28 PMID: 4179938
  77. Structural analysis of nucleolar precursors of ribosomal ribonucleic acid. Comparative hybridizations of nucleolar and ribosomal ribonucleic acid with nucleolar deoxyribonucleic acid.
    J Biol Chem. 1970 Apr 25;245(8):1962-9 PMID: 4314935
  78. Effect of phytohemagglutinin on lymphocytes from patients with chronic lymphocytic leukemia.
    Arch Pathol. 1967 Jan;83(1):58-63 PMID: 6015848
  79. RNA synthesis in Taper hepatoma and mouse-liver cells.
    Biochim Biophys Acta. 1969 Sep 17;190(1):30-7 PMID: 4309826
  80. [Desoxyribonucleic acid polymerase in the human leukocytes. Enzyme activity in leukemia and virus infections].
    Klin Wochenschr. 1968 Apr 15;46(8):407-13 PMID: 5247007
  81. Structure and synthesis of ribosomal RNA.
    Annu Rev Biochem. 1970;39:183-226 PMID: 4920820
  82. Oligonucleotides of ribosomal 28 S RNA in human leukemic cells and normal lymphocytes.
    Cancer Res. 1974 Jun;34(6):1281-8 PMID: 4524044
  83. Sedimentation characteristics of rapidly labelled RNA from HeLa cells.
    Biochem Biophys Res Commun. 1962 Jun 4;7:486-90 PMID: 14498283
  84. Human leukemic cells. Fractionation and characterization of ribonucleic acids.
    Exp Cell Res. 1972 Nov;75(1):39-46 PMID: 4508391
  85. IMMUNOLOGIC AND CYTOGENETIC STUDIES OF CHRONIC LYMPHOCYTIC LEUKEMIC CELLS.
    Blood. 1965 Aug;26:121-32 PMID: 14332475
  86. Comparative studies on the ultrastructure of nucleoli in human lymphosarcoma cells and leukemic lymphocytes.
    Cancer Res. 1970 Apr;30(4):1149-55 PMID: 5537320
  87. Defective rRNA synthesis in human leukaemic blast cells?
    Nature. 1974 Apr 19;248(5450):673-5 PMID: 4524580
  88. [The morphological proof of two lymphocyte systems in man].
    Klin Wochenschr. 1959 Sep 15;37:941-6 PMID: 13829855
  89. The effect of phytohemagglutinin on ribonucleic acid synthesis and histone acetylation in equine leukocytes.
    J Cell Biol. 1967 Nov;35(2):477-82 PMID: 6066061
  90. RNA synthesis and histone acetylation during the course of gene activation in lymphocytes.
    Proc Natl Acad Sci U S A. 1966 Apr;55(4):805-12 PMID: 5219687
  91. [Intranuclear bodies of alveolar histiocytes in the rabbit, in vivo and in vitro: fibrillar and nucleolar bodies].
    C R Acad Sci Hebd Seances Acad Sci D. 1972 Aug 16;275(7):851-5 PMID: 4629189
  92. Changes in hybridizable nuclear RNA during the neoplastic development of mouse mammary cells.
    Cancer Res. 1971 Apr;31(4):427-32 PMID: 5553688
  93. Fractionation of mouse deoxyribonucleic acid on hydroxyapatite.
    Nature. 1965 Dec 18;208(5016):1175-9 PMID: 5870316
  94. Synthesis of acid-soluble proteins by the lymphocytes of chronic lymphocytic leukemia.
    J Lab Clin Med. 1966 May;67(5):757-63 PMID: 5946034
  95. The ultrastructure of phytohemagglutinin (PHA) stimulated lymphocytes of chronic lymphatic leukemia.
    Blood. 1969 Aug;34(2):179-90 PMID: 5794115
  96. Chromatin structures in ring-shaped nucleoli of human lymphocytes.
    Exp Cell Res. 1968 Sep;52(1):112-28 PMID: 5675555
  97. [On the classification of lymphocytes].
    Med Klin. 1963 Apr 26;58:706-9 PMID: 13970263
  98. Competition hybridization studies on rapidly sedimenting RNA of acute leukemia blast cells.
    Eur J Cancer. 1972 Dec;8(6):653-8 PMID: 4510359
  99. Characterization of human leukemia and Burkitt lymphoma cells by their acidic nuclear protein profiles.
    Cancer Res. 1972 May;32(5):1009-17 PMID: 4502171
  100. Populations of repeated DNA sequences in the human genome.
    J Mol Biol. 1972 Feb 14;63(3):323-34 PMID: 5014924
  101. Electrophoretic mobility and N-acetyl neuraminic acid content of human normal and leukemic lymphocytes and granulocytes.
    Blood. 1970 Jan;35(1):12-22 PMID: 5412671
  102. Studies of the dynamics of ribonucleic acid formation.
    J Biol Chem. 1958 Jul;233(1):197-202 PMID: 13563468
  103. EFFECTS OF PHYTOHAEMAGGLUTININ ON BLOOD-CULTURES OF CHRONIC LYMPHOCYTIC LEUKAEMIAS.
    Lancet. 1964 Mar 21;1(7334):667-8 PMID: 14107951
  104. Possible control of lymphocyte growth at the level of ribosome assembly.
    Nature. 1968 Oct 12;220(5163):196-7 PMID: 5684842
  105. DNA repair in human leukaemic lymphocytes.
    Nat New Biol. 1972 Nov 22;240(99):114-6 PMID: 4509023
  106. Circular dimer and catenate forms of mitochondrial DNA in human leukaemic leucocytes.
    Nature. 1967 Nov 18;216(5116):652-7 PMID: 6082459
  107. Ribsomal ribonucleic acid production and growth regulation in human lymphocytes.
    J Biol Chem. 1969 Apr 10;244(7):1946-52 PMID: 5780847
Article Info
Journal
Klinische Wochenschrift
Abbr.
Klin Wochenschr
ISSN
0023-2173
DOI
10.1007/BF01468619
Published
1974-12-01
Pages
1093-102
Language
ger
Region
Germany
NLM ID
2985205R
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01468619
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2