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PMID: 5301388 Published · ppublish English Journal Article

Leprosy and genetics. A review of past research with remarks concerning future investigations.

Bulletin of the World Health Organization ·Vol. 37 ·No. 3 ·1967-00-00 ·Pages 461-76

Beiguelman B

Abstract

The few geneticists who are interested in leprosy have been working in this field only since 1962, and have made little progress in solving the problems presented by susceptibility to this disease.This paper reviews the research that has been conducted, with particular reference to the search for associations between leprosy and certain genetic markers. In each area, the advantages and limitations of different techniques are described, and attention is drawn to sources of bias that may invalidate many of the results that have been published. Of particular interest is the discussion of a new technique for evaluating resistance to-leprosy. The proposed technique is based upon the in vitro transformation of blood monocytes into macrophages, and the observation of their behaviour against Mycobacterium leprae.

MeSH Terms
Humans Leprosy/genetics Research
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Beiguelman B
References (52)
52 references, click to expand
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Article Info
Journal
Bulletin of the World Health Organization
Abbr.
Bull World Health Organ
ISSN
0042-9686
Published
1967-00-00
Pages
461-76
Language
English
Region
Switzerland
NLM ID
7507052
PMCID
PMC2554265
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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