Analysis of antigenic determinants in cholera enterotoxin and heat-labile enterotoxins from human and porcine enterotoxigenic Escherichia coli.
Antigenic determinants of cholera enterotoxin (CT) and heat-labile enterotoxin from a human strain (LTh) and a porcine strain (LTp) were analyzed by Ouchterlony double-gel diffusion test against anti-CT, anti-LTh, and anti-LTp, which were treated by immunoaffinity column chromatography. The results showed the existence of the following antigenic determinants: (i) antigenic determinants unique to CT, LTh, and LTp, respectively; (ii) an antigenic determinant common to CT, LTh, and LTp; (iii) an antigenic determinant common to CT and LTh, but not LTp; and (iv) an antigenic determinant common to LTh and LTp, but not CT. On the basis of these results, an antigenic scheme for CT, LTh, and LTp is proposed.
14 references, click to expand
-
Pathogenesis of experimental cholera. Preparation and isolation of choleragen and choleragenoid.J Exp Med. 1969 Jul 1;130(1):185-202 PMID: 4978880
-
A heat-labile enterotoxin from strains of Eschericha coli enteropathogenic for pigs.J Infect Dis. 1969 Oct;120(4):419-26 PMID: 4898783
-
Immunologic cross-reactions of enterotoxins from Escherichia coli and Vibrio cholerae.J Infect Dis. 1973 Feb;127(2):164-70 PMID: 4570128
-
Identification of enterotoxigenic Escherichia coli and serum antitoxin activity by the vascular permeability factor assay.Infect Immun. 1973 Nov;8(5):731-5 PMID: 4584049
-
Immunological study of the heat-labile enterotoxins of Escherichia coli and Vibrio cholerae.Infect Immun. 1974 Mar;9(3):564-70 PMID: 4206029
-
Immunological cross-reactivity between a heat-labile enterotoxin(s) of Escherichia coli and subunits of Vibrio cholerae enterotoxin.Infect Immun. 1978 Sep;21(3):1036-9 PMID: 361573
-
Demonstration of shared and unique immunological determinants in enterotoxins from Vibrio cholerae and Escherichia coli.Infect Immun. 1978 Dec;22(3):709-13 PMID: 83301
-
Isolation and characterization of homogeneous heat-labile enterotoxins with high specific activity from Escherichia coli cultures.Infect Immun. 1979 Jun;24(3):760-9 PMID: 89088
-
Modified Elek test for detection of heat-labile enterotoxin of enterotoxigenic Escherichia coli.J Clin Microbiol. 1981 Jan;13(1):1-5 PMID: 6780599
-
Isolation of special antibodies which react only with homologous enterotoxins from Vibrio cholerae and Enterotoxigenic Escherichia coli.Infect Immun. 1981 Nov;34(2):333-6 PMID: 6171516
-
Immunological nonidentity of heat-labile enterotoxins from human and porcine enterotoxigenic Escherichia coli.Infect Immun. 1981 Nov;34(2):337-40 PMID: 6171517
-
In vitro formation of hybrid toxins between subunits of Escherichia coli heat-labile enterotoxin and those of cholera enterotoxin.Infect Immun. 1981 Nov;34(2):341-6 PMID: 7309227
-
Comparison of heat-labile enterotoxins from porcine and human strains of Escherichia coli.Infect Immun. 1982 Apr;36(1):215-20 PMID: 6176542
-
Molecular heterogeneity of heat-labile enterotoxins from human and porcine enterotoxigenic Escherichia coli.Infect Immun. 1982 Nov;38(2):444-8 PMID: 7141704
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: [email protected]
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
