Home LiteratureArticle Details
PMID: 6203126 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Clustered genes for human U2 RNA.

Westin G, Zabielski J, Hammarström K, Monstein HJ, Bark C, Pettersson U

Abstract

Genes for the human small nuclear RNA U2 are present within 6.2-kilobase-pair-long tandem repeats. The haploid human genome contains approximately 20 such repeats, organized in one or a few very large clusters.

MeSH Terms
Base Sequence Cloning, Molecular DNA Restriction Enzymes DNA, Recombinant Genes Genetic Linkage Humans Nucleic Acid Hybridization RNA/genetics RNA, Small Nuclear Repetitive Sequences, Nucleic Acid
Chemicals
DNA, Recombinant RNA, Small Nuclear RNA DNA Restriction Enzymes
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Westin G
Zabielski J
Hammarström K
Monstein H J
Bark C
Pettersson U
References (31)
31 references, click to expand
  1. Human DNA sequences complementary to the small nuclear RNA U2.
    Nucleic Acids Res. 1981 Dec 11;9(23):6323-38 PMID: 6172777
  2. Primary and secondary structure of U2 snRNA.
    Nucleic Acids Res. 1981 Nov 11;9(21):5645-58 PMID: 6796940
  3. Human U1 loci: genes for human U1 RNA have dramatically similar genomic environments.
    Cell. 1982 May;29(1):257-64 PMID: 6179629
  4. Transcription of a gene for human U1 small nuclear RNA.
    Cell. 1982 May;29(1):265-74 PMID: 6179630
  5. Characterization of small nuclear RNA U1 gene candidates and pseudogenes from the human genome.
    J Mol Appl Genet. 1981;1(2):117-25 PMID: 6180116
  6. SnRNAs, SnRNPs, and RNA processing.
    Annu Rev Biochem. 1982;51:617-54 PMID: 6180681
  7. Sea urchin small nuclear RNA genes are organized in distinct tandemly repeating units.
    Nucleic Acids Res. 1982 Dec 11;10(23):7677-88 PMID: 6185926
  8. Pseudogenes for human small nuclear RNA U3 appear to arise by integration of self-primed reverse transcripts of the RNA into new chromosomal sites.
    Cell. 1983 Feb;32(2):461-72 PMID: 6186397
  9. Structural analysis of gene loci for rat U1 small nuclear RNA.
    Nucleic Acids Res. 1983 Mar 25;11(6):1791-801 PMID: 6188110
  10. Genes and pseudogenes for mouse U1 and U2 small nuclear RNAs.
    J Biol Chem. 1983 Jul 10;258(13):8151-5 PMID: 6190807
  11. Loci for human U1 RNA: structural and evolutionary implications.
    J Mol Biol. 1983 Jun 25;167(2):245-57 PMID: 6191037
  12. Isolation and characterization of three cloned fragments of human DNA coding for tRNAs and small nuclear RNA U1.
    Gene. 1983 May-Jun;22(2-3):211-7 PMID: 6192042
  13. Molecular cloning and characterization of a gene for rat U2 small nuclear RNA.
    J Mol Biol. 1983 Aug 15;168(3):579-94 PMID: 6193279
  14. Isolation and characterization of two linked mouse U1b small nuclear RNA genes.
    Nucleic Acids Res. 1983 Sep 24;11(18):6255-70 PMID: 6194507
  15. Isolation and characterization of Drosophila melanogaster U2 small nuclear RNA genes.
    J Mol Biol. 1983 Sep 25;169(3):691-705 PMID: 6195341
  16. Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes.
    EMBO J. 1983;2(11):1883-91 PMID: 6196192
  17. A candidate gene for human U1 RNA.
    EMBO J. 1982;1(1):133-7 PMID: 6201353
  18. A pseudogene for human U4 RNA with a remarkable structure.
    EMBO J. 1982;1(6):737-9 PMID: 6203736
  19. Human U1 RNA pseudogenes may be generated by both DNA- and RNA-mediated mechanisms.
    Mol Cell Biol. 1982 Jul;2(7):815-28 PMID: 6085956
  20. Mapping of simian virus 40 early functions on the viral chromosome.
    J Virol. 1973 Sep;12(3):653-8 PMID: 4355862
  21. Detection of specific sequences among DNA fragments separated by gel electrophoresis.
    J Mol Biol. 1975 Nov 5;98(3):503-17 PMID: 1195397
  22. The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.
    Cell. 1978 Dec;15(4):1157-74 PMID: 728996
  23. Are snRNPs involved in splicing?
    Nature. 1980 Jan 10;283(5743):220-4 PMID: 7350545
  24. Partial nucleotide sequence of the 300-nucleotide interspersed repeated human DNA sequences.
    Nature. 1980 Mar 27;284(5754):372-4 PMID: 6244506
  25. Sequencing end-labeled DNA with base-specific chemical cleavages.
    Methods Enzymol. 1980;65(1):499-560 PMID: 6246368
  26. A mechanism for RNA splicing.
    Proc Natl Acad Sci U S A. 1980 Apr;77(4):1877-9 PMID: 6246511
  27. Abundant pseudogenes for small nuclear RNAs are dispersed in the human genome.
    Proc Natl Acad Sci U S A. 1981 Feb;78(2):810-4 PMID: 6165010
  28. Comparison of RNase T1 fingerprints of U1, U2, and U3 small nuclear RNA's of HeLa cells, human normal fibroblasts, and Novikoff hepatoma cells.
    Cancer Res. 1981 Jun;41(6):2215-20 PMID: 6165460
  29. Organization of sequences related to U6 RNA in the human genome.
    Nucleic Acids Res. 1981 Jul 24;9(14):3379-88 PMID: 6169006
  30. Novel models for RNA splicing that involve a small nuclear RNA.
    Proc Natl Acad Sci U S A. 1981 Jul;78(7):4471-4 PMID: 6170064
  31. Direct repeats flank three small nuclear RNA pseudogenes in the human genome.
    Cell. 1981 Oct;26(1 Pt 1):11-7 PMID: 6173130
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1984-06-00
Pages
3811-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC345310
Subset
IM
Databases
GENBANK
M12526, M19204, M19205, M19206
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]