Comparative in vitro activities of teichomycin and vancomycin alone and in combination with rifampin and aminoglycosides against staphylococci and enterococci.

Antimicrobial agents and chemotherapy ·Vol. 25 ·No. 4 ·1984-04-00 ·Pages 411-2

Tuazon CU, Miller H

Abstract

The activity of teichomycin A2 was compared with that of vancomycin in vitro against clinical isolates of staphylococci and enterococci. Teichomycin A2 was more active than vancomycin active against all isolates tested. Synergistic studies also demonstrated that teichomycin A2 combined with rifampin is more active than vancomycin combined with rifampin against Staphylococcus aureus and Staphylococcus epidermidis isolates. Teichomycin A2, either singly or in combination with an aminoglycoside, was more active against Streptococcus faecalis isolates.

MeSH Terms

Aminoglycosides/pharmacology Anti-Bacterial Agents/pharmacology Drug Synergism Enterococcus faecalis/drug effects Microbial Sensitivity Tests Rifampin/pharmacology Staphylococcus/drug effects Staphylococcus aureus/drug effects Teicoplanin Vancomycin/pharmacology

Chemicals

Aminoglycosides Anti-Bacterial Agents Teicoplanin Vancomycin Rifampin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Tuazon C U

Miller H

References (11)

11 references, click to expand

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Comparison of the in vitro activities of teichomycin A2 and vancomycin against staphylococci and enterococci.
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In vitro activity of teichomycin and vancomycin alone and in combination with rifampin.
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Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.25.4.411

Published

1984-04-00

Pages

411-2

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC185541

Subset

External Links

PubMed source DOI: 10.1128/AAC.25.4.411 PMC Full Text View journal details

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Comparative in vitro activities of teichomycin and vancomycin alone and in combination with rifampin and aminoglycosides against staphylococci and enterococci.

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