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PMID: 6287927 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Molecular epidemiology of beta-lactamase-specifying plasmids of Haemophilus ducreyi.

Antimicrobial agents and chemotherapy ·Vol. 21 ·No. 6 ·1982-06-00 ·Pages 857-63

Brunton J, Meier M, Ehrman N, Maclean I, Slaney L, Albritton WL

Abstract

We have studied the genetic basis of beta-lactamase production in eight strains of Haemophilus ducreyi isolated in diverse areas of the world. Beta-lactamase production in all strains was mediated by plasmids having a molecular mass of either 5.7 or 7.0 megadaltons. Plasmids of 5.7 megadaltons were shown to carry the entire sequence of pFA7, the beta-lactamase specifying plasmid found in isolates of Neisseria gonorrhoeae epidemiologically linked to West Africa. Plasmids of 7.0 megadaltons were shown to carry the entire sequence of pFA3, the beta-lactamase specifying plasmid found in Far Eastern isolates of N. gonorrhoeae. Both groups of H. ducreyi plasmids were shown to carry physically complete and functional TnA sequences. Thus we have identified two types of H. ducreyi beta-lactamase plasmid which are identical to the two types of N. gonorrhoeae beta-lactamase plasmid, except that they carry complete TnA sequences.

MeSH Terms
Base Sequence DNA Restriction Enzymes Escherichia coli/genetics Haemophilus ducreyi/drug effects,enzymology R Factors beta-Lactamases/genetics
Chemicals
DNA Restriction Enzymes beta-Lactamases
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Brunton J
Meier M
Ehrman N
Maclean I
Slaney L
Albritton W L
References (28)
28 references, click to expand
  1. Plasmid transformation in Haemophilus influenzae.
    J Bacteriol. 1981 Feb;145(2):1099-101 PMID: 6970194
  2. The genetic basis of the spread of beta-lactamase synthesis among plasmid-carrying bacteria.
    Philos Trans R Soc Lond B Biol Sci. 1980 May 16;289(1036):349-59 PMID: 6109330
  3. Molecular nature of a plasmid specifying beta-lactamase production in Haemophilus ducreyi.
    J Bacteriol. 1981 Dec;148(3):788-95 PMID: 6273382
  4. Mobilization of nonconjugative antibiotic resistance plasmids in Haemophilus ducreyi.
    J Bacteriol. 1982 Feb;149(2):726-32 PMID: 6276368
  5. Intraspecific and intergeneric mobilization of non-conjugative resistance plasmids by a 24.5 megadalton conjugative plasmid of Neisseria gonorrhoeae.
    J Gen Microbiol. 1981 Jul;125(1):123-9 PMID: 6801191
  6. Plasmid-mediated sulfonamide resistance in Haemophilus ducreyi.
    Antimicrob Agents Chemother. 1982 Jan;21(1):159-65 PMID: 6282205
  7. A membrane-filter technique for the detection of complementary DNA.
    Biochem Biophys Res Commun. 1966 Jun 13;23(5):641-6 PMID: 5963888
  8. Dependence of the melting temperature of DNA on salt concentration.
    Biopolymers. 1965;3(2):195-208 PMID: 5889540
  9. Nucleic acid reassociation in formamide.
    Biochemistry. 1969 Aug;8(8):3289-95 PMID: 4980190
  10. Isolation of an E. coli strain with a mutation affecting DNA polymerase.
    Nature. 1969 Dec 20;224(5225):1164-6 PMID: 4902142
  11. Beginning a genetic analysis of conjugational transfer determined by the F factor in Escherichia coli by isolation and characterization of transfer-deficient mutants.
    J Bacteriol. 1971 May;106(2):529-38 PMID: 4929865
  12. Nonchromosomal antibiotic resistance in bacteria: genetic transformation of Escherichia coli by R-factor DNA.
    Proc Natl Acad Sci U S A. 1972 Aug;69(8):2110-4 PMID: 4559594
  13. Nucleotide sequence of the rightward operator of phage lambda.
    Proc Natl Acad Sci U S A. 1975 Mar;72(3):1184-8 PMID: 1055375
  14. Detection of specific sequences among DNA fragments separated by gel electrophoresis.
    J Mol Biol. 1975 Nov 5;98(3):503-17 PMID: 1195397
  15. Simple agarose gel electrophoretic method for the identification and characterization of plasmid deoxyribonucleic acid.
    J Bacteriol. 1976 Sep;127(3):1529-37 PMID: 821935
  16. Characterization of an R-plasmid associated with ampicillin resistance in Shigella dysenteriae type 1 isolated from epidemics.
    Antimicrob Agents Chemother. 1977 Mar;11(3):553-8 PMID: 324394
  17. Relationships among some R plasmids found in Haemophilus influenzae.
    J Bacteriol. 1977 Jul;131(1):356-62 PMID: 301523
  18. Molecular characterization of two beta-lactamase-specifying plasmids isolated from Neisseria gonorrhoeae.
    J Bacteriol. 1977 Aug;131(2):557-63 PMID: 407214
  19. Evidence for two distinct types of penicillinase-producing Neisseria gonorrhoeae.
    Lancet. 1977 Nov 12;2(8046):993-5 PMID: 72949
  20. Antimicrobial susceptibility of Haemophilus ducreyi.
    Antimicrob Agents Chemother. 1978 Apr;13(4):608-12 PMID: 307364
  21. Regional preference of insertion of Tn501 and Tn802 into RP1 and its derivatives.
    Mol Gen Genet. 1978 Nov 9;166(3):313-20 PMID: 105244
  22. Plasmid-mediated ampicillin resistance in Haemophilus ducreyi.
    Antimicrob Agents Chemother. 1979 Feb;15(2):294-9 PMID: 311618
  23. Transformation-derived Neisseria gonorrhoeae plasmids with altered structure and function.
    J Bacteriol. 1979 May;138(2):510-8 PMID: 108261
  24. Molecular characterization of a small Haemophilus influenzae plasmid specifying beta-lactamase and its relationship to R factors from Neisseria gonorrhoeae.
    J Gen Microbiol. 1979 Mar;111(1):223-31 PMID: 110907
  25. TEM-type beta-lactamase production in Haemophilus ducreyi.
    Antimicrob Agents Chemother. 1980 May;17(5):897-900 PMID: 6967297
  26. Linkage map of Escherichia coli K-12, edition 6.
    Microbiol Rev. 1980 Mar;44(1):1-56 PMID: 6997720
  27. Penicillinase-producing Neisseria gonorrhoeae in the Netherlands: epidemiology and genetic and molecular characterization of their plasmids.
    Antimicrob Agents Chemother. 1980 Nov;18(5):789-97 PMID: 6778387
  28. Molecular epidemiology of Haemophilus ducreyi infections.
    Ann Intern Med. 1981 Sep;95(3):315-8 PMID: 6973943
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.21.6.857
Published
1982-06-00
Pages
857-63
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC182035
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.21.6.857 PMC Full Text View journal details
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