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PMID: 6319373 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Escherichia coli K-12 gyrB gene product is involved in the lethal effect of the ligts2 mutant of bacteriophage Mu.

Journal of bacteriology ·Vol. 157 ·No. 2 ·1984-02-00 ·Pages 665-8

Ghelardini P, Liebart JC, Marchelli C, Pedrini AM, Paolozzi L

Abstract

Mu ligts2 mutants, defective for development and integration, show a high killing effect on the infected host. A number of survivors to Mu ligts2 infection were analyzed; they are characterized by nonpermissivity for both development and lysogenization of bacteriophage Mu. Bacteriophages D108 and P1 are also inhibited in these strains as is transposon Tn9. The corresponding mutation site was mapped at 82 min and identified with the Escherichia coli gyrB site.

MeSH Terms
Coliphages/genetics DNA Topoisomerases, Type II/genetics Escherichia coli/enzymology,genetics Genes Genes, Bacterial Genes, Lethal Genes, Viral Lysogeny Mutation Phenotype
Chemicals
DNA Topoisomerases, Type II
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Ghelardini P
Liebart J C
Marchelli C
Pedrini A M
Paolozzi L
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24 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.157.2.665-668.1984
Published
1984-02-00
Pages
665-8
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC215300
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.157.2.665-668.1984 PMC Full Text View journal details
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